Merck
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16033

Sigma-Aldrich

1,2-Propanediol

meets analytical specification of Ph. Eur., BP, USP, ≥99.5%

Synonym(s):
1,2-PDO, Propylene glycol
Linear Formula:
CH3CH(OH)CH2OH
CAS Number:
Molecular Weight:
76.09
Beilstein:
1340498
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

vapor density

2.62 (vs air)

Quality Level

vapor pressure

0.08 mmHg ( 20 °C)

assay

≥99.5%

form

liquid

autoignition temp.

779 °F

quality

meets analytical specification of Ph. Eur., BP, USP

shelf life

24 mo.

expl. lim.

12.5 %

impurities

acidic reac. impurities, complies
organic volatile impurities, complies (GC)
oxidizing substances, complies
reducing matter, complies
residual solvents, complies
≤0.0005% heavy metals (as Pb)
≤0.002% free alkali (as NaOH)
≤0.003% free acid (as CH3COOH)
≤0.2% water (Karl Fischer)

ign. residue

≤0.005% (as SO4)

refractive index

n20/D 1.431-1.433
n20/D 1.432 (lit.)

bp

187 °C (lit.)

mp

−60 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

suitability

complies for appearance of solution

SMILES string

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

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General description

1,2-Propanediol is an important petrochemical that can be prepared by the hydrogenolysis of glycerol. It is mainly used as a cryoprotectant for biological samples and also as an additive in food, cosmetic and pharmaceutical industries.
1,2-Propanediol is an 1,2-alkanediol. It can be obtained from glycerol, via hydrogenolysis in the presence of Ru/C and Amberlyst ion-exchange resins.

Application

1,2-Propanediol may be employed as a cryoprotective agent for the preservation (by cooling to sub-zero temperatures) of human embryos and and oocytes (human and mouse).

Packaging

bottled under inert gas

Other Notes

The article number 16033-4X5L will be discontinued. Please order the single bottle 16033-5L which is physically identical with the same exact specifications.
The article number 16033-6X1L will be discontinued. Please order the single bottle 16033-1L which is physically identical with the same exact specifications.
The article number 16303-4X2.5L-R will be discontinued. Please order the single bottle 16303-2.5L-R which is physically identical with the same exact specifications.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

219.2 °F - closed cup

Flash Point(C)

104 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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