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Safety Information

MAB1308

Sigma-Aldrich

Mouse Anti-Human IgG2 Antibody, clone HP6002, Fc

clone HP6002, Chemicon®, from mouse

Synonym(s):

Anti-Anti-CD32, Anti-Anti-CD32B, Anti-Anti-FCG2, Anti-Anti-FCGR2, Anti-Anti-FCGR2C, Anti-Anti-FcGRIIB, Anti-Anti-FcRII-c, Anti-Anti-FcgammaRIIb, Anti-Anti-IGFR2

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.46

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

secondary antibodies

clone

HP6002, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
radioimmunoassay: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_001002273.1
NM_001002274.1
NM_001002275.1
NM_004001.3

UniProt accession no.

P31994

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... FCGR2B(2213)

Related Categories

Specificity

Human IgG2 Fc. ELISA Specificity: (Hamilton et al., 1987) human IgG subclass 1-0.02% human IgG subclass 2- 100% human IgG subclass 3- 0.01%

human IgG subclass 4- 0.01% Isoelectric Focusing: mean pI 7.1

Application

This Mouse anti-Human IgG2 Antibody, clone HP6002, Fc is validated for use in ELISA, RIA, WB for the detection of Human IgG2.
This antibody employed as both a capture antibody and a detection antibody for human IgG2 in enzyme linked immunosorbent assays, radio-immunoassay and EIA affinity immunoblots (Papadea et al., 1985; Hamilton, et al., 1987).

Final working dilutions must be determined by end user.

Linkage

Replaces: 411462-200UG

Physical form

Format: Purified
Purified Immunoglobulin. Liquid in 0.02M Phosphate buffer, pH=7.6, 0.25M NaCl containing 0.1% sodium azide.

Storage and Stability

Maintain at 2-8°C for up to one year in undiluted aliquots.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB1308:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Elizabeth H Aitken et al.
eLife, 10 (2021-06-29)
Plasmodium falciparum causes placental malaria, which results in adverse outcomes for mother and child. P. falciparum-infected erythrocytes that express the parasite protein VAR2CSA on their surface can bind to placental chondroitin sulfate A. It has been hypothesized that naturally acquired
Suzanne E Barbour et al.
Infection and immunity, 70(6), 2780-2786 (2002-05-16)
Several lines of evidence indicate that the monocytes of subjects with localized juvenile periodontitis (LJP) are functionally distinct from cells of age- and race-matched nonperiodontitis (NP) subjects. Among the abnormalities are the propensity to secrete large amounts of prostaglandin E(2)
F Brière et al.
The Journal of experimental medicine, 179(2), 757-762 (1994-02-01)
During antigen-induced immune responses, human B cells switch isotype from immunoglobulin M (IgM)-IgD to IgG1-4, IgA1-2, or IgE. In the human, no cytokines have yet been demonstrated to act as switch factors for IgG1, IgG2, and IgG3. In this paper
Monoclonal antibody-based solid-phase immunoenzymometric assays for quantifying human immunoglobulin G and its subclasses in serum.
Papadea, C, et al.
Clinical Chemistry, 31, 1940-1945 (1985)
S Langy et al.
Infection and immunity, 66(6), 2854-2858 (1998-05-29)
The full-length cDNA sequence encoding Brugia malayi L3 paramyosin has been isolated by immunoscreening a cDNA library with a mouse antiserum raised against Wuchereria bancrofti L3 infective larvae. A recombinant truncated form of paramyosin was expressed as a glutathione S-transferase

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