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Key Documents

Safety Information

AB3704

Sigma-Aldrich

Anti-Orexin-A Antibody

serum, Chemicon®

Synonym(s):

Anti-NRCLP1, Anti-OX, Anti-PPOX

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

NCBI accession no.

NM_001524.1

UniProt accession no.

O43612

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... PPOX(5498)

Specificity

Orexin-A.

Immunogen

Synthetic peptide corresponding to the C-terminal portion of the bovine Orexin-A peptide.

Application

Detect Orexin-A using this Anti-Orexin-A Antibody validated for use in IH.
Immunohistochemistry: 1:1,000-1:2,000. The antibody shows intense labeling of Orexin-A neurons with low background.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
CNS Control of Metabolism

Circadian Rhythm & Sleep

Physical form

Rabbit serum. Lyophilized. Reconstitute with 50 mL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.

Storage and Stability

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

AB3704:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Projections from the paraventricular nucleus of the thalamus to the forebrain, with special emphasis on the extended amygdala.
Sa Li,Gilbert J Kirouac
The Journal of Comparative Neurology null
Retrograde study of hypocretin-1 (orexin-A) projections to subdivisions of the dorsal raphe nucleus in the rat.
Hyun S Lee, Seung H Park, Wu C Song, Barry D Waterhouse
Brain Research null
T Nambu et al.
Brain research, 827(1-2), 243-260 (1999-05-13)
Orexin (ORX)-A and -B are recently identified neuropeptides, which are specifically localized in neurons within and around the lateral hypothalamic area (LHA) and dorsomedial hypothalamic nucleus (DMH), the regions classically implicated in feeding behavior. Here, we report a further study
Distribution of orexinergic neurons and their terminal networks in the brains of two species of African mole rats.
Adhil Bhagwandin,Kjell Fuxe,Nigel C Bennett,Paul R Manger
Journal of Chemical Neuroanatomy null
Hannah Bruguier et al.
The Journal of comparative neurology, 528(17), 2956-2977 (2020-04-09)
The human claustrum, a major hub of widespread neocortical connections, is a thin, bilateral sheet of gray matter located between the insular cortex and the striatum. The subplate is a largely transient cortical structure that contains some of the earliest
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