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230734

Sigma-Aldrich

Chorionic Gonadotropin, Human Urine, Standard Grade

Chorionic Gonadotropin, Human Urine, Standard Grade, CAS 9002-61-3, is a native glycoprotein hormone that is synthesized by chorionic tissue of the placenta and found in urine during pregnancy.

Synonym(s):

Chorionic Gonadotropin, Human Urine, Standard Grade, hCG

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352202

Quality Level

description

Protein Concentration/ Report Result, weight

sterility

non-sterile

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

off-white

pI 

4.9

solubility

water: soluble

shipped in

ambient

storage temp.

−20°C

Related Categories

General description

Native, human chorionic gonadotropin from urine. Glycoprotein hormone synthesized by chorionic tissue of the placenta and found in urine during pregnancy. Also present in body fluids of patients with trophoblastic disease and ovarian tumors.
Native, human chorionic gonadotropin from urine. Glycoprotein hormone synthesized by chorionic tissue of the placenta and found in urine during pregnancy. Also present in body fluids of patients with trophoblastic disease and ovarian tumors. ≥3000 IU/mg (Who 3rd IS 75/537).

Biochem/physiol Actions

≥3000 IU/mg solids (Who 3rd IS 75/537)

Warning

Toxicity: Carcinogenic / Teratogenic (D)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of reconstituted solutions. Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Chandy, K.G., et al. 1990. Science247, 973.
Smith, D.B. and Johnson, K.S. 1988. Gene67, 31.
Tempel, B.L., et al. 1988. Nature332, 837.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Kimberly Mitchell et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(23), 12772-12783 (2020-05-30)
The luteinizing hormone surge is essential for fertility as it triggers ovulation in females and sperm release in males. We previously reported that secretoneurin-a, a neuropeptide derived from the processing of secretogranin-2a (Scg2a), stimulates luteinizing hormone release, suggesting a role
Xuzhe Zhang et al.
Molecular biology and evolution, 37(2), 507-523 (2019-10-22)
Evolution of highly invasive placentation in the stem lineage of eutherians and subsequent extension of pregnancy set eutherians apart from other mammals, that is, marsupials with short-lived placentas, and oviparous monotremes. Recent studies suggest that eutherian implantation evolved from marsupial

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