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178196

Sigma-Aldrich

α1-Antichymotrypsin, Human Plasma

Acute-phase protein present at ~45 mg/100 ml in plasma.

Synonym(s):

α1-Antichymotrypsin, Human Plasma, α₁-Achy, α₁-1X, α₁-1X-Glycoprotein

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About This Item

CAS Number:
141176-92-3
MDL number:
MFCD00162030
UNSPSC Code:
12352202
NACRES:
NA.77

Quality Level

100

Assay

≥95% (SDS-PAGE)

form

solid

specific activity

≥85%, pH 7.4, 25 °C (using Suc-Ala-Ala-Pro-Phe-pNA as substrate, inhibition of cathepsin G)

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

aqueous buffer: soluble

shipped in

ambient

storage temp.

−20°C

General description

Acute-phase protein present at 45 mg/100 ml in plasma. Specific inhibitor of chymotrypsin-like serine proteinases.
Acute-phase protein present at ~45 mg/100 ml in plasma. Specific inhibitor of chymotrypsin-like serine proteinases. Molecular weight ranges from 65,000-68,000 daltons.
M.W. 65,000-68,000.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Chymotrypsin-like serine proteases
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Physical form

Lyophilized from 150 mM NaCl, 20 mM Tris-HCl, pH 7.4.

Preparation Note

Please refer to vial label for lot-specific volume prior to lyophilization.
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for at up to 6 months at -20°C.

Other Notes

Desrochers, P.E., et al. 1992. J. Biol. Chem.267, 5005.
Rayford, A., et al. 1992. J.Neurochem.58, 88.
Travis, J., et al. 1978. Biochemistry17, 5651.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

178196-100RUG:
178196-1MG:
178196-1RMG:
178196-100UG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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