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Safety Information

1.06574

SAFC

di-Sodium hydrogen phosphate heptahydrate

EMPROVE® ESSENTIAL, DAC, USP

Pharma Manufacturing

Synonym(s):

Sodium phosphate dibasic heptahydrate, Disodium hydrogen phosphate heptahydrate, Disodium phosphate

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About This Item

Linear Formula:
Na2HPO4 · 7H2O
CAS Number:
7782-85-6
Molecular Weight:
268.07
MDL number:
MFCD00149180
UNSPSC Code:
12352302
EC Index Number:
231-448-7

Agency

DAC
USP

Quality Level

500

vapor density

4.9 (vs air)

product line

EMPROVE® ESSENTIAL

form

solid

pH

8.7-9.3 (25 °C, 50 g/L in H2O)

mp

48 °C (Elimination of water of crystallisation)

solubility

154 g/L

density

1.68 g/mL at 25 °C (lit.)

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-30°C

SMILES string

O.O.O.O.O.O.O.[Na+].[Na+].OP([O-])([O-])=O

InChI

1S/2Na.H3O4P.7H2O/c;;1-5(2,3)4;;;;;;;/h;;(H3,1,2,3,4);7*1H2/q2*+1;;;;;;;;/p-2

InChI key

PYLIXCKOHOHGKQ-UHFFFAOYSA-L

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

di-Sodium hydrogen phosphate heptahydrate is typically used as a phosphate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

1065740000:
1065747025:
1065749100:
1065748888:
1065749029BWT:
1065749999:
1065749336:
1065749008:
1065749028:
1065740001:
1065749029:
CO1E1065741000:
1065749013:
1065741000:
1065749501:
CO1E1065749029:
1065740050:
1065749012:
1065749038:
1065741000BWT:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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