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Safety Information

1.04871

SAFC

Potassium dihydrogen phosphate

crystalline, EMPROVE® ESSENTIAL, Ph. Eur., BP, JPC, NF, E 340

Pharma Manufacturing

Synonym(s):

Potassium phosphate monobasic, mono-Potassium orthophosphate, Potassium biphosphate, Potassium phosphate monobasic, Monopotassium phosphate, Potassium dihydrogen phosphate, prim.-Potassium phosphate

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About This Item

Linear Formula:
KH2PO4
CAS Number:
7778-77-0
Molecular Weight:
136.09
MDL number:
MFCD00011401
UNSPSC Code:
12352302
E Number:
E340
EC Index Number:
231-913-4

Agency

BP
JPC
NF
Ph. Eur.

Quality Level

500

product line

EMPROVE® ESSENTIAL

Assay

≥99.0% dry basis (alkalimetric)
98.0-100.5% (alkalimetric)

form

crystalline
solid

pH

4.2-4.6 (20 °C, 20 g/L in H2O)

mp

252.6 °C (lit.)

solubility

208 g/L

density

2.338 g/mL at 25 °C (lit.)

application(s)

liquid formulation
ophthalmics
pharmaceutical
solid formulation

storage temp.

2-30°C

SMILES string

[K+].OP(O)([O-])=O

InChI

1S/K.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1

InChI key

GNSKLFRGEWLPPA-UHFFFAOYSA-M

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Potassium hydrogen phosphate is a commonly used ingredient in both food and pharmaceutical applications. In pharmaceutical applications, potassium hydrogen phosphate is primarily used as a buffering agent.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

1048712222:
1048710000:
CO1E1048719029:
1048719029:
1048719052:
1048710701:
1048710702:
1048715000:
CO1E1048715000:
1048719999:
1048715715:
1048719053:
CO1E1048719050:
1048719050:
1048715000BWT:
1048719014:
1.04871.9029.BWT:
1048711000BWT:
1048719012:
1048711000:
1048716378:
1048710703:
1048719100:
1048710001:
1048719050BWT:
MX11048710001:
1048715894:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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