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Safety Information

07-239

Sigma-Aldrich

Anti-mGluR7 Antibody

Upstate®, from rabbit

Synonym(s):

Anti-GLUR7, Anti-MGLU7, Anti-MGLUR7, Anti-NEDSHBA, Anti-PPP1R87

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_000831

UniProt accession no.

Q14831

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GRM7(2917)

Specificity

mGluR7

Immunogen

peptide (C-NSPAAKKKYVSYNN) corresponding to amino acids 899-912 of human mGluR7

Application

Detect mGluR7 using this Anti-mGluR7 Antibody validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Vesicular Trafficking

Neurodegenerative Diseases

Quality

routinely evaluated by immunoblot on rat brain microsomal preparation

Target description

97kDa

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

07-239:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses.
Paulo S Pinheiro, David Perrais, Francoise Coussen, Jacques Barhanin, Bernhard Bettler et al.
Proceedings of the National Academy of Sciences of the USA null
Nicole M Fisher et al.
JCI insight, 6(4) (2021-01-22)
The metabotropic glutamate receptor 7 (mGlu7) is a G protein-coupled receptor that has been recently linked to neurodevelopmental disorders. This association is supported by the identification of GRM7 variants in patients with autism spectrum disorder, attention deficit hyperactivity disorder, and
Anatomy and function of group III metabotropic glutamate receptors in gastric vagal pathways.
Richard L Young,Nicole J Cooper,L Ashley Blackshaw
Neuropharmacology null
Tevye Jason Stachniak et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(39), 8150-8162 (2021-08-13)
Throughout development, neuronal identity is controlled by key transcription factors that determine the unique properties of a cell. During embryogenesis, the transcription factor Prox1 regulates VIP-positive cortical interneuron migration, survival, and connectivity. Here, we explore the role of Prox1 as
James A Daniel et al.
eLife, 6 (2017-06-10)
SUMO1-conjugation of proteins at neuronal synapses is considered to be a major post-translational regulatory process in nerve cell and synapse function, but the published evidence for SUMO1-conjugation at synapses is contradictory. We employed multiple genetic mouse models for stringently controlled
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