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N-115

Supelco

Naloxone-D5 solution

1.0 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C19H16NO4D5
CAS Number:
1261079-38-2
Molecular Weight:
332.41
MDL number:
MFCD08063611
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

[2H]\C([2H])=C(/[2H])C([2H])([2H])N1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@]2(O)CCC4=O)c35

InChI

1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1/i1D2,2D,8D2

InChI key

UZHSEJADLWPNLE-HEEDNVRVSA-N

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General description

A stable-labeled internal standard suitable for numerous quantitative LC/MS and GC/MS applications in forensic analysis, clinical toxicology testing, pharmaceutical analysis and isotope dilution methods. Naloxone is an opiate drug used to counter the effects of opioid overdose.

Application


  • Naloxone-D₅ analytical standard: Naloxone-D₅ is a stable isotopic label extensively utilized as an analytical standard in mass spectrometry to study the pharmacokinetics of naloxone. This application is critical for understanding naloxone′s metabolism and clearance rates in opioid overdose scenarios, thereby enhancing therapeutic strategies and drug safety (Xu et al., 2018).


Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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IMPN-007-04

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N-004

Naloxone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

N-063

Naloxone-D5 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

N-924

Nalorphine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

N-099

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N-103

6α-Naloxol solution, 1.0 mg/mL in methanol, certified reference material, Cerilliant®

N-109

Naloxone-D5-3-β-D-glucuronide solution, 100 μg/mL in methanol: water (9:1), certified reference material, ampule of 1 mL, Cerilliant®

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Alcohols
Hazardous rank II

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

N-115-1ML:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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