IMPN-007-04
Naloxone N-oxide solution
100 μg/mL in acetonitrile: water (1:1), ampule of 1 mL, certified reference material, Cerilliant®
Synonym(s):
Naloxone N-oxide solution
About This Item
Recommended Products
grade
certified reference material
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
100 μg/mL in acetonitrile: water (1:1)
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
forensics and toxicology
format
single component solution
storage temp.
−20°C
SMILES string
Oc1ccc2C[C@@H]3[C@]4(O)CCC(=O)[C@@H]5Oc1c2[C@]45CC[N@@+]3([O-])CC=C
InChI
1S/C19H21NO5/c1-2-8-20(24)9-7-18-15-11-3-4-12(21)16(15)25-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-,20?/m1/s1
InChI key
GAUIBVINJLVYRY-QBFPIVRFSA-N
General description
Application
- Nociceptive Descending Inhibition Restoration: Naloxone N-oxide has been studied in the context of traumatic brain injury in rats, focusing on its role in restoring nociceptive descending inhibition through the periaqueductal gray. This application contributes to our understanding of opioid receptor antagonist research in the recovery of neurological functions (Irvine et al., 2024).
- Opioid Receptor Research: Research on Naloxone N-oxide involves exploring its interaction with opioid receptors, particularly in the context of stress-induced reinstatement of drug preferences. This underscores its importance in studies related to opioid receptor antagonist mechanisms in addiction and stress response (Nygard et al., 2016).
- Quantitative Biochemical Assays: The use of Naloxone N-oxide in liquid chromatography-tandem mass spectrometry assays exemplifies its role in the simultaneous quantification of buprenorphine, naloxone, and their metabolites. This is crucial for pharmacokinetic analysis and monitoring drug metabolism in clinical settings (Swortwood et al., 2016).
Legal Information
related product
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
55.4 °F - closed cup
Flash Point(C)
13 °C - closed cup
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
PDSCL
Deleterious substance
FSL
Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water soluble liquid
ISHL Indicated Name
Substances Subject to be Indicated Names
ISHL Notified Names
Substances Subject to be Notified Names
JAN Code
IMPN-007-04-CC:
IMPN-007-04-CHK:
IMPN-007-04-1ML:
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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