G-006

GHB-d₆ sodium salt solution

1.0 mg/mL in methanol (as salt), ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₄HNaO₃D₆
• CAS Number: 362049-53-4
• Molecular Weight: 132.12
• EC Number: 200-659-6
• MDL number: MFCD01861535
• UNSPSC Code: 41116107
• PubChem Substance ID: 329799796
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)
• concentration: 1.0 mg/mL in methanol (as salt)
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −20°C
• SMILES string: OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([O-])=O.[Na+]
• InChI: 1S/C4H8O3.Na/c5-3-1-2-4(6)7;/h5H,1-3H2,(H,6,7);/q;+1/p-1/i1D2,2D2,3D2;
• InChI key: XYGBKMMCQDZQOZ-LRDWTYOMSA-M

Description

General description

GHB, or γ-hydroxybutyrate, is a central nervous system depressant sold under the brand name Xyrem^® and used medically to treat narcolepsy, excessive daytime sleepiness and in rare circumstances, alcoholism. GHB is also used recreationally as an intoxicant and date rape drug. This internal standard is suitable for quantitation of GHB levels in urine, serum, plasma, or oral fluid by LC/MS or GC/MS for urine drug testing, clinical toxicology, forensic analysis, or isotope dilution methods.

Application

• Analysis of biofluids for gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL) by headspace GC-FID and GC-MS: This study discusses the methodological approaches to analyze biofluids for GHB and its precursor gamma-butyrolactone (GBL) using headspace gas chromatography (GC) with flame ionization detection (FID) and mass spectrometry (MS). These techniques provide precise quantification and detection of GHB and GBL, contributing significantly to forensic and clinical toxicology. The analysis ensures reliable results, making it essential for accurate diagnosis and legal investigations (LeBeau MA, Montgomery MA, Miller ML, Burmeister SG, 2000).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Xyrem is a registered trademark of JPI Commercial, LLC

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup