Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

Safety Information

857136P

Avanti

18:1 BMP (R,R)

sn-(1-oleoyl-2-hydroxy)-glycerol-3-phospho-sn-3′-(1′-oleoyl-2′-hydroxy)-glycerol (ammonium salt), powder

Synonym(s):

lysobisphosphatidic acid; LBPA

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C42H82NO10P
CAS Number:
1246303-13-8
Molecular Weight:
792.07
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (BMP (contains 30% positional isomers), TLC)

form

powder

packaging

pkg of 1 × 5 mg (857136P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 857136P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP(OC[C@]([H])(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)([O-])=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

General description

Bis(monoacylglycerol)phosphate (BMP) is an acidic phospholipid. It is mostly located in the lysosomal and endosomal compartments within cells.

Biochem/physiol Actions

Bis(monoacylglycerol)phosphate (BMP) regulates late endosomes/lysosomes (LE/Lys) degradation pathway. It also modulates cholesterol homeostasis and trafficking of lysosomal enzymes. BMP is implicated in the digestion and recycling of membranous materials and synthesis of intra luminal vesicles.

Packaging

5 mL Clear Glass Sealed Ampule (857136P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

857136P-5MG:
857136P-VAR:
857136P-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ion mobility and tandem mass spectrometry of phosphatidylglycerol and bis (monoacylglycerol) phosphate (BMP)
Hankin JA, et al.
International Journal of Mass Spectrometry, 378, 255-263 (2015)
Nanjun Liu et al.
Toxicology and applied pharmacology, 279(3), 467-476 (2014-06-27)
The inability to routinely monitor drug-induced phospholipidosis (DIPL) presents a challenge in pharmaceutical drug development and in the clinic. Several nonclinical studies have shown di-docosahexaenoyl (22:6) bis(monoacylglycerol) phosphate (di-22:6-BMP) to be a reliable biomarker of tissue DIPL that can be
Elena Zaitseva et al.
PLoS pathogens, 6(10), e1001131-e1001131 (2010-10-16)
Many enveloped viruses invade cells via endocytosis and use different environmental factors as triggers for virus-endosome fusion that delivers viral genome into cytosol. Intriguingly, dengue virus (DEN), the most prevalent mosquito-borne virus that infects up to 100 million people each

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service