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Safety Information

QBD10275

Sigma-Aldrich

MAL-dPEG®8-acid

>95% (HPLC)

Synonym(s):

Carboxy-PEG-maleimide, Carboxy-PEG8-maleimide, MAL-PEG400-acid, MAL-PEG8-COOH, MAL-PEG8-acid

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About This Item

Empirical Formula (Hill Notation):
C26H44N2O13
Molecular Weight:
592.63
MDL number:
MFCD13184956
UNSPSC Code:
12352106
NACRES:
NA.22

Assay

>95% (HPLC)

form

solid or viscous liquid

reaction suitability

reaction type: Pegylations

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

Features and Benefits

MAL-dPEG8-acid is a monodisperse crosslinker that joins sulfhydryl groups to free amines through a single molecular weight polyethylene glycol (PEG) chain of discrete length. The linker is 34 atoms and 38.8 Å long. The maleimidopropyl moiety reacts with sulfhydryl groups via a Michael addition reaction. The propionic acid terminus of the molecule reacts directly with free amines using EDC or another carbodiimide to form amide bonds. Alternatively, activation of the propionic acid group with N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), or some other acylating agent permits amide bond formation under mild, controlled conditions.

Legal Information

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

QBD10275-100MG:

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