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CF0004

Sigma-Aldrich

Alcohol Togni-(PhSCF2CF2)-reagent

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About This Item

Linear Formula:
C17H15F4IOS
CAS Number:
1836233-11-4
MDL number:
MFCD31618525
UNSPSC Code:
12352200

form

solid

reaction suitability

reaction type: C-C Bond Formation

storage temp.

−20°C

Application

Alcohol Togni-(PhSCF2CF2)-reagent is an electrophilic hypervalent iodine-fluoroalkyl reagent introducing the phenylsulfanyltetrafluoroethyl fragment. A phenylsulfanyltetrafluoroethyl moiety incorporated in the substrate can be treated with tributyltin hydride and generate the corresponding fluoroalkyl radical. If the substrate lacks any olefine, it can be reduced to tetrafluoroethyl group whereas if the substrate contains an olefine in the correct spatial orientation, it can lead to an intramolecular cyclisation affording tetrafluorinated cyclic structures.

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Other Notes

Technology Spotlight: Fluoroalkylation: Expansion of Togni Reagents

Legal Information

Product of CF Plus Chemicals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

CF0004-250MG:

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Articles

Fluoroalkylation: Expansion of Togni Reagents

The fluoroalkylation toolbox now includes Togni reagents, hypervalent iodine perfluoroalkylation reagents, fluoroalkyl bromides, silanes, carboxylates, and sulfonyl fluorides for late stage fluoroalkylation.

Fluoroalkylation: Expansion of Togni Reagents

The fluoroalkylation toolbox now includes Togni reagents, hypervalent iodine perfluoroalkylation reagents, fluoroalkyl bromides, silanes, carboxylates, and sulfonyl fluorides for late stage fluoroalkylation.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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