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Safety Information

934283

Sigma-Aldrich

4-(Aminoethyl)-1-N-Boc-piperidine

≥95.0%

Synonym(s):

1-tert-Butoxycarbonyl-4-piperidineethanamine, 2-(N-tert-Butoxycarbonyl-4-piperidinyl)ethylamine

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About This Item

Empirical Formula (Hill Notation):
C12H24N2O2
CAS Number:
Molecular Weight:
228.33
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21

Quality Level

Assay

≥95.0%

form

semisolid

color

off-white to light yellow

storage temp.

2-8°C

SMILES string

O=C(OC(C)(C)C)N1CCC(CCN)CC1

Application

A semi-flexible linker useful for PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of PROTACs may impact degradation kinetics as well as drug design (absorption; distribution; metabolism; excretion; and toxicity; ADMET) properties of PROTACs.

Technology Spotlight:

Degrader Building Blocks for Targeted Protein Degradation

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Legal Information

PROTAC® is a registered trademark of Arvinas Operations; Inc.; and is used under license.
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

934283-VAR:
934283-100MG:
934283-BULK:


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