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Safety Information

809926

Sigma-Aldrich

1α,25-Dihydroxyvitamin D3-26,26,26,27,27,27-d6 solution

100 μg/mL in ethanol, ≥98 atom % D, ≥95% (CP)

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About This Item

Empirical Formula (Hill Notation):
C27D6H38O3
CAS Number:
78782-99-7
Molecular Weight:
422.67
EC Number:
200-578-6
MDL number:
MFCD15071365
UNSPSC Code:
12352106
PubChem Substance ID:
329769198
NACRES:
NA.12

isotopic purity

≥98 atom % D

Quality Level

200

Assay

≥95% (CP)

form

liquid

concentration

100 μg/mL in ethanol

technique(s)

mass spectrometry (MS): suitable

color

colorless

mass shift

M+6

storage temp.

−20°C

SMILES string

C=C1[C@@H](O)C[C@H](O)C/C1=C/C=C2C(CCC3[C@H](C)CCCC(O)(C([2H])([2H])[2H])C([2H])([2H])[2H])[C@]3(C)CCC/2

InChI

1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23?,24?,25+,27-/m1/s1/i3D3,4D3

InChI key

GMRQFYUYWCNGIN-LPTLAYIMSA-N

Related Categories

General description

1α,25-Dihydroxyvitamin D3 [1,25(OH)2D3], also known as calcitriol, plays a role in calcium and phosphate metabolism in humans. It also regulates insulin secretion and induces cellular differentiation.
1α,25-Dihydroxyvitamin D3-26,26,26,27,27,27-d6 is a deuterated vitamin D3 wherein C-26 and C-27 carbon methyl protons are replaced by deuterium.

Application

1α,25-Dihydroxyvitamin D3-26,26,26,27,27,27-d6 can be used as an analytical standard for the quantitative analysis of dihydroxyvitamin D3 concentration in human serum via LC-MS.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

57.2 °F

Flash Point(C)

14 °C

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Alcohols
Hazardous rank II

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

809926-VAR:
809926-BULK:
809926-1ML:
809926-1ML-PW:

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Certificates of Analysis (COA)

Lot/Batch Number
MBBC8289
MBBC7776
MBBC6443
MBBC4027
MBBC1437

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Quantification of 1, 25-dihydroxyvitamin D2 and D3 in serum using liquid chromatography-tandem mass spectrometry
Clinical Applications of Mass Spectrometry in Biomolecular Analysis, 63(2), 291-300 (2016)
Paola Illesca et al.
Food & function, 11(10), 9086-9102 (2020-10-08)
Nutritional interventions are promising tools for the prevention of obesity. The n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) docosahexaenoic acid (DHA) modulates immune and metabolic responses while the antioxidant hydroxytyrosol (HT) prevents oxidative stress (OS) in white adipose tissue (WAT).
The emerging role of vitamin D3 in women′s health
Khadilkar, SS
The Journal of Obstetrics and Gynecology of India, 63(2), 147?150-147?150 (2013)
Vitamin D3: a helpful immuno-modulator
Di R, et al.
Immunology, 134(2), 123-139 (2011)

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