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Safety Information

518093

Sigma-Aldrich

Ethyl (triphenylphosphoranylidene)pyruvate

95%

Synonym(s):

2-Ethoxycarbonyl-2-oxoethylidenetriphenylphosphorane, NSC 647346, [(Carboxycarbonyl)methylene]triphenylphosphorane ethyl ester

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About This Item

Linear Formula:
(C6H5)3P=CHCOCO2C2H5
CAS Number:
Molecular Weight:
376.38
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:
NACRES:
NA.22

Assay

95%

reaction suitability

reaction type: C-C Bond Formation

mp

175 °C (dec.) (lit.)

functional group

ester
ketone
phosphine

SMILES string

CCOC(=O)C(=O)C=P(c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C23H21O3P/c1-2-26-23(25)22(24)18-27(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21/h3-18H,2H2,1H3

InChI key

OQLOPRPWPANPIE-UHFFFAOYSA-N

Application

Reactant for:
  • Wittig condensation
  • Chemoenzymic preparation of hexafluoroleucine and tetrafluoroleucine

Reactant for synthesis of:
  • Ahiral and chiral cyclic dehydro-α-amino acid derivatives through nucleophilic addition
  • Peptidyl α-keto-based inhibitors of cruzain
  • Deoxyfluoro-L-arabinofuranosyl triazole nucleoside derivatives with antiviral activity
  • Anti-human immunodificiency virus analogs

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

518093-VAR:
518093-25G:
518093-BULK:


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