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Safety Information

479160

Sigma-Aldrich

(R)-(+)-4-Hydroxy-2-pyrrolidinone

97%

Synonym(s):

(R)-β-Hydroxy-γ-butyrolactam

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About This Item

Empirical Formula (Hill Notation):
C4H7NO2
CAS Number:
22677-21-0
Molecular Weight:
101.10
Beilstein:
1524193
MDL number:
MFCD00273364
UNSPSC Code:
12352005
PubChem Substance ID:
24871603
NACRES:
NA.22

Quality Level

100

Assay

97%

optical activity

[α]23/D +43°, c = 1 in ethanol

mp

156-159 °C (lit.)

functional group

hydroxyl

SMILES string

O[C@H]1CNC(=O)C1

InChI

1S/C4H7NO2/c6-3-1-4(7)5-2-3/h3,6H,1-2H2,(H,5,7)/t3-/m1/s1

InChI key

IOGISYQVOGVIEU-GSVOUGTGSA-N

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

479160-1G:
479160-5G:
479160-VAR:
479160-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
MKBZ1072V
MKBQ7264V
MKBP3761V
MKBN9565V
MKBL8897V

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G Di Silvestro et al.
Journal of pharmaceutical sciences, 82(7), 758-760 (1993-07-01)
The phase diagram of (R)- and (S)-4-hydroxy-2-pyrrolidone presents a conglomerate in the racemic mixture. The enthalpy of melting extrapolated by the Schröder-van Laar-Le Chatelier equation [change in enthalpy (delta H) = 28410 J/mol; melting temperature (TA) = 429.9 K; solidus

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