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440183

Sigma-Aldrich

(3-Chloropropyl)trimethoxysilane

≥97%

Synonym(s):

δ-Chloropropyltrimethoxysilane, (γ-Chloropropyl)trimethoxysilane, (3-Chloropropyl)trimethoxysilane, 3-(Trimethoxysilyl)propyl chloride

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About This Item

Linear Formula:
Cl(CH2)3Si(OCH3)3
CAS Number:
Molecular Weight:
198.72
Beilstein:
969627
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23

Assay

≥97%

form

liquid

refractive index

n20/D 1.419 (lit.)

bp

195 °C/750 mmHg (lit.)

density

1.09 g/mL at 25 °C (lit.)

SMILES string

CO[Si](CCCCl)(OC)OC

InChI

1S/C6H15ClO3Si/c1-8-11(9-2,10-3)6-4-5-7/h4-6H2,1-3H3

InChI key

OXYZDRAJMHGSMW-UHFFFAOYSA-N

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General description

(3-Chloropropyl)trimethoxysilane (CPTMS) is an organo-silane which forms a self-assembled monolayer (SAMs) that facilitates the surface modification of different bio-and nano- materials.

Application

(3-Chloropropyl)trimethoxysilane may be used in the synthesis of octakis(3-chloropropyl)octasilsesquioxane.{35}
CPTMS can be used to silanize a variety of nanoparticles like carbon nanotubes (CNT) and silica nanoparticles (SiO2) for different applications like development for molecularly imprinted polymers for protein detection and fabrication of mesoporous silica(organic-inorganic hybrid). It may be used to functionalize silica-iron oxide nanoparticles which can be used as catalysts for the synthesis of pyrano(3,2−c:5,6−c′)dichromene-6,8-dione derivatives.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

161.1 °F - closed cup

Flash Point(C)

71.7 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

440183-VAR:
440183-100ML:
440183-1L:
440183-BULK:


Certificates of Analysis (COA)

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Gabriela Corazza et al.
Journal of chromatography. A, 1513, 42-50 (2017-07-25)
In this study, the hybrid material 3-n-propyl(3-methylpyridinium) silsesquioxane chloride (Si3Py
DABCO-modified super-paramagnetic nanoparticles as an efficient and water-compatible catalyst for the synthesis of pyrano (3, 2-c: 5, 6-c') dichromene-6, 8-dione derivatives under mild reaction conditions.
Heydari Z, et al.
Applied Organometallic Chemistry, 205(4), e4561-e4561 (2018)
Ke-Feng Wang et al.
Chembiochem : a European journal of chemical biology, 19(7), 654-659 (2018-01-16)
2,5-Furandicarboxylic acid (FDCA) is a bio-based platform chemical for the production of polyethylene furanoate (PEF) and other valuable furanic chemicals. A magnetic laccase catalyst with (2,2,6,6-tetramethyl-piperidin-1-yl)oxyl (TEMPO) as the mediator has the remarkable capability of oxidizing 5-hydroxymethylfurfural (HMF) to 2,5-furandicarboxylic
One-pot synthesis and modification of silica nanoparticles with 3-chloropropyl-trimethoxysilane assisted by microwave irradiation.
De Conto JF, et al.
Chemical Engineering Communications , 205(4), 533-537 (2018)
Durali Mendil et al.
Food chemistry, 221, 1394-1399 (2016-12-17)
A novel and simple solid phase extraction method was improved and recommended for selenium. Silica gel was modified with 2,6-diamino-4-phenil-1,3,5-triazine and characterized by FTIR, SEM and elemental analysis and used adsorbent for column solid phase extraction of selenium ions. The

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