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367508

Sigma-Aldrich

7-Methoxy-2-naphthol

98%

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About This Item

Linear Formula:
CH3OC10H6OH
CAS Number:
5060-82-2
Molecular Weight:
174.20
Beilstein:
2207279
MDL number:
MFCD00075494
UNSPSC Code:
12352100
PubChem Substance ID:
24862762
NACRES:
NA.22

Assay

98%

mp

116-119 °C (lit.)

SMILES string

COc1ccc2ccc(O)cc2c1

InChI

1S/C11H10O2/c1-13-11-5-3-8-2-4-10(12)6-9(8)7-11/h2-7,12H,1H3

InChI key

UNFNRIIETORURP-UHFFFAOYSA-N

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General description

7-Methoxy-2-naphthol is a 7-substituted-2-naphthol. Crystal structure of 7-methoxy-2-naphthol has been reported. Reaction of 7-methoxy-2-naphthol with N-methyl-N-phenylhydrazine under thermal conditions has been reported.

Application

7-Methoxy-2-naphthol may be used in the synthesis of new 1H-benzo[f]chromene derivatives. It may be used in the synthesis of 7-methoxy-2-naphthyl (MN)-derived xylosides in which the methoxy group served as a marker for NMR characterization and UV detection.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

367508-5G:
367508-25G:
367508-VAR:
367508-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
BCBB2701V
BCBB2700V
BCBB2700
BCBB2701
10028PH

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7-Methoxy-2-naphthol.
Prince P, et al.
Acta Crystallographica Section C, Crystal Structure Communications, 47(10), 2218-2220 (1991)
Sandrine Gulberti et al.
The Journal of biological chemistry, 280(2), 1417-1425 (2004-11-04)
We determined whether the two major structural modifications, i.e. phosphorylation and sulfation of the glycosaminoglycan-protein linkage region (GlcAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1), govern the specificity of the glycosyltransferases responsible for the biosynthesis of the tetrasaccharide primer. We analyzed the influence of C-2 phosphorylation of
Synthesis of 9-methoxy and 9-acetoxy-3-amino-1-(4-methoxyphenyl)-1H-benzo [f] chromene-2-carbonitriles via 2-(imino-piperidin-1-yl-methyl)-3-(4-methoxyphenyl) acrylonitrile as intermediate.
El-Agrody AM, et al.
Zeitschrift fur Naturforschung, B: Chemical Sciences, 57(5), 579-585 (2002)
Qiang Tang et al.
Journal of the American Chemical Society, 130(18), 5840-5841 (2008-04-15)
An unexpected reaction of N,N-disubstituted hydrazine with naphthol and its analogues under simply thermal conditions has been disclosed. 2-Naphthol reacted with various N,N-disubstituted hydrazines under argon to afford 1-amino-2-naphthol and the corresponding secondary amines in excellent yields. Ortho amination of

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