Skip to Content
Merck
All Photos(3)

Key Documents

View All Documentation

Safety Information

228753

Sigma-Aldrich

Isonicotinoyl chloride hydrochloride

95%

Synonym(s):

(Chlorocarbonyl)-4-(pyridinyl) monohydrochloride, 4-(Chloroformyl)pyridinium hydrochloride, 4-Nicotinoyl chloride hydrochloride, 4-Pyridinecarboxylic acid chloride hydrochloride, Isonicotinic acid chloride hydrochloride, Isonicotinyl chloride hydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C6H4ClNO · HCl
CAS Number:
39178-35-3
Molecular Weight:
178.02
EC Number:
254-331-2
MDL number:
MFCD00012830
UNSPSC Code:
12352100
PubChem Substance ID:
24853709
NACRES:
NA.22

Quality Level

200

Assay

95%

mp

159-161 °C (lit.)

solubility

methanol: soluble 50 mg/mL, clear to hazy, colorless to light yellow

functional group

acyl chloride

SMILES string

Cl[H].ClC(=O)c1ccncc1

InChI

1S/C6H4ClNO.ClH/c7-6(9)5-1-3-8-4-2-5;/h1-4H;1H

InChI key

BNTRVUUJBGBGLZ-UHFFFAOYSA-N

Application

Isonicotinoyl chloride hydrochloride was used in the synthesis of 7,16-diisonicotinoyltetraaza[14]annulene.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

228753-5G:
228753-25G:
228753-BULK:
228753-VAR:
228753-100G:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCG4741
MKBR3151V
MKBL8503V
MKBJ0276V
MKBH3134V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Imir G Metushi et al.
Chemical research in toxicology, 25(11), 2567-2576 (2012-09-29)
Isoniazid (INH) is associated with serious liver injury and autoimmunity. Classic studies in rats indicated that a reactive metabolite of acetylhydrazine is responsible for the covalent binding and toxicity of INH. Studies in rabbits suggested that hydrazine might be the
Synthesis and characterization of 7, 16-dinicotinoyl-and 7, 16-diisonico-tinoyltetraaza [14] annulene and their nickel (II) and copper (II) complexes.
Sakata K and Itoh M.
Journal of Heterocyclic Chemistry, 29(4), 921-926 (1992)
Juan Le et al.
Journal of lipid research, 60(5), 1058-1064 (2019-03-25)
Vitamin D metabolite analysis possessed significant clinical value for the pediatric department. However, invasive venipuncture sampling and high blood consumption inflicted much suffering on patients. For alleviation, we carried out a LC-MS method for 25-hydroxyvitamin D quantification in only 3

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service