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Safety Information

213381

Sigma-Aldrich

Nicotinoyl chloride hydrochloride

97%

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About This Item

Empirical Formula (Hill Notation):
C6H4ClNO · HCl
CAS Number:
Molecular Weight:
178.02
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

powder

mp

151-157 °C (lit.)

functional group

acyl chloride

SMILES string

Cl[H].ClC(=O)c1cccnc1

InChI

1S/C6H4ClNO.ClH/c7-6(9)5-2-1-3-8-4-5;/h1-4H;1H

InChI key

MSYBLBLAMDYKKZ-UHFFFAOYSA-N

Application

Nicotinoyl chloride hydrochloride was used in the preparation of :
  • 1-[5-O-tert-butyldimethylsilyl-2-deoxy-2-fluoro-3-O-(3-pyridylcarbonyl)-β-D-ribofuranosyl]uracil
  • 7,16-dinicotinoylated and/or 7,16-diisonicotinoylated compounds via reaction with tetraaza[14]annulene and its complexes
  • bis(ethylenedithio)tetrathiafulvalene derivatives

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

213381-BULK:
213381-VAR:
213381-25G:


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Shuang Li et al.
Journal of the mechanical behavior of biomedical materials, 102, 103521-103521 (2019-12-27)
In this research, a bio-based monomer 1,3-bis(methacryloyloxy)propyl-carbonyl- hexylpyridinium bromide (QANMA) that derived from niacin was synthesized and incorporated into Bisphenol A glycidyl methacrylate (Bis-GMA)/triethylene glycol dimethacrylate (TEGDMA) (50 wt/50 wt) with a series of mass fraction as antibacterial agent. The double bond
K W Morin et al.
Carbohydrate research, 249(1), 109-116 (1993-10-18)
1-(2-Deoxy-2-fluoro-beta-D-ribofuranosyl-(E)-5-(2-iodovinyl)uracil (IVFRU) was coupled to a dihydropyridine <---> pyridinium salt redox chemical-delivery system (CDS) via a cleavable sugar-ester linkage as a site-directed approach to increase diffusion of the parent nucleoside into the central nervous system. Treatment of 1-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)uracil with Bu(t)Me(2)SiCl
Synthesis of bis(ethylenedithio) tetrathiafulvalene derivatives with metal ion ligating centres.
Griffiths J-P, et al.
Tetrahedron Letters, 44(15), 31327-31331 (2003)
Wenqiang Tan et al.
Carbohydrate polymers, 157, 236-243 (2016-12-19)
Based on cuprous-catalyzed azide-alkyne cycloaddition (CuAAC), starch derivative bearing 1,2,3-triazole and pyridine (II) was prepared and subsequently followed by alkylation with iodomethane to synthesize starch derivative bearing 1,2,3-triazolium and pyridinium (III). The antifungal activities of starch derivatives against Colletotrichum lagenarium
Synthesis and characterization of 7, 16-dinicotinoyl-and 7, 16-diisonico-tinoyltetraaza [14] annulene and their nickel (II) and copper (II) complexes.
Sakata K and Itoh M.
Journal of Heterocyclic Chemistry, 29(4), 921-926 (1992)

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