Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

Safety Information

161969

Sigma-Aldrich

Triethylenetetramine tetrahydrochloride

97%

Synonym(s):

Cuprior, Trientine tetrahydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
NH2CH2CH2(NHCH2CH2)2NH2 · 4HCl
CAS Number:
4961-40-4
Molecular Weight:
292.08
EC Number:
225-604-3
MDL number:
MFCD00012890
UNSPSC Code:
12352100
PubChem Substance ID:
24849963
NACRES:
NA.22

Assay

97%

mp

269-270 °C (lit.)

functional group

amine

SMILES string

Cl.Cl.Cl.Cl.NCCNCCNCCN

InChI

1S/C6H18N4.4ClH/c7-1-3-9-5-6-10-4-2-8;;;;/h9-10H,1-8H2;4*1H

InChI key

OKHMDSCYUWAQPT-UHFFFAOYSA-N

Related Categories

General description

Triethylenetetramine tetrahydrochloride is a copper-chelating agent

Application

Triethylenetetramine tetrahydrochloride was used as primary amine displacer in affinity chromatography.

Biochem/physiol Actions

Triethylenetetramine tetrahydrochloride induces apoptosis of acinar cells of the pancreas in male Fischer 344 rats.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335,H351

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

161969-25G:
161969-100G:
161969-BULK:
161969-VAR:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
75598MJV
75598MJ
00830EH
10923BX
04511MD

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

Tris(2-aminoethyl)amine 96%

Sigma-Aldrich

225630

Tris(2-aminoethyl)amine

1-(2-Aminoethyl)piperazine 99%

Sigma-Aldrich

A55209

1-(2-Aminoethyl)piperazine

S Kishimoto et al.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 45(8), 489-495 (1994-04-01)
Male Fischer 344 rats weighing 80-90 g were fed on a copper-depleted diet supplemented with 0.6% triethylenetetramine tetrahydrochloride (a copper chelator), and the death of pancreatic acinar cells of these rats was investigated morphologically and biochemically. The weight of the
Structural characteristics of low-molecular-mass displacers for cation-exchange chromatography: II. Role of the stationary phase.
Shukla AA, et al.
Journal of Chromatography A, 872(2), 295-310 (1998)
Concetta R Capo et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 44, 225-232 (2017-10-03)
The secoiridoid oleuropein is a non-flavonoid polyphenol, found in the fruit, leaves and food derivatives from Olea europea. Like other polyphenols it shows a very low toxicity towards healthy tissues and a protective action against cancer or neurodegeneration, but its

Global Trade Item Number

SKUGTIN
161969-100G
161969-25G4061832106229

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service