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90460

Sigma-Aldrich

Triethylenetetramine

≥97.0% (T)

Synonym(s):

TETA, DEH 24, EPH 925

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About This Item

Linear Formula:
NH2CH2CH2(NHCH2CH2)2NH2
CAS Number:
112-24-3
Molecular Weight:
146.23
Beilstein:
605448
EC Number:
203-950-6
MDL number:
MFCD00008169
UNSPSC Code:
12352100
PubChem Substance ID:
57653396
NACRES:
NA.22

vapor density

~5 (vs air)

Quality Level

200

vapor pressure

<0.01 mmHg ( 20 °C)

Assay

≥97.0% (T)

form

liquid

refractive index

n20/D 1.496 (lit.)

bp

266-267 °C (lit.)

mp

12 °C (lit.)

density

0.982 g/mL at 25 °C (lit.)

SMILES string

NCCNCCNCCN

InChI

1S/C6H18N4/c7-1-3-9-5-6-10-4-2-8/h9-10H,1-8H2

InChI key

VILCJCGEZXAXTO-UHFFFAOYSA-N

Gene Information

human ... TERT(7015)

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Application

Triethylenetetramine has been used as an additive to enhance the peak resolution ability of capillary zone electrophoresis (CZE) running buffer system to separate and quantitate the monoclonal antibodies by the CZE method. It may be used for the amination of polyacrylonitrile fibers to form novel fiber catalysts for Knoevenagel condensation in aqueous media. TETA also acts as a copper (II)-selective chelator. It may also be used as a growth-orientator in the formation of 1D zinc sulfide nanoarchitectures.

Signal Word

Danger

Hazard Statements

H312,H314,H317,H411

Hazard Classifications

Acute Tox. 4 Dermal - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

264.2 °F

Flash Point(C)

129 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

PRTR

Class II Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water soluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

90460-INTR:
90460-10ML:4548173348643
90460-VAR:
90460-50ML:4548173348650
90460-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Triethylenetetramine (TETA)-assisted synthesis, dynamic growth mechanism, and photoluminescence properties of radial single-crystalline ZnS nanowire bundles.
Liu J
Journal of Crystal Growth, 311(5), 1423-1429 (2009)
Efficient and reusable amine-functionalized polyacrylonitrile fiber catalysts for Knoevenagel condensation in water.
Li G
Green Chemistry, 14(8), 2234-2242 (2012)
Metabolomic analysis of rat serum in streptozotocin-induced diabetes and after treatment with oral triethylenetetramine (TETA).
Ugarte M
Genome Medicine, 4(4), 35-35 (2012)
Development and validation of a rapid capillary zone electrophoresis method for determining charge variants of mAb.
Shi Y
Journal of Chromatography. B, Biomedical Applications, 906, 63-68 (2012)
Marc Cerrada-Gimenez et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(12), 2242-2249 (2011-09-01)
Triethylenetetramine (TETA) is an efficient copper chelator that has versatile clinical potential. We have recently shown that spermidine/spermine-N(1)-acetyltransferase (SSAT1), the key polyamine catabolic enzyme, acetylates TETA in vitro. Here, we studied the metabolism of TETA in three different mouse lines:
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