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Merck

Reactions of difluorocarbene with organozinc reagents.

Organic letters (2013-02-02)
Vitalij V Levin, Artem A Zemtsov, Marina I Struchkova, Alexander D Dilman
ABSTRACT

Reactions of difluorocarbene with benzyl and alkylzinc halides leading to fluorinated organozinc species have been described. The generated α-difluorinated organozinc reagents are reasonably stable in solution and can be quenched with external electrophiles (iodine, bromine, proton), affording compounds containing the CF(2) fragment.

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Sigma-Aldrich
Bromina, ACS reagent, ≥99.5%
Sigma-Aldrich
Bromina, reagent grade
Sigma-Aldrich
Bromina, ≥99.99% trace metals basis