1619006

Spironolactone

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: 4-Pregnen-21-oic acid-17α-ol-3-one-7α-thiol γ-lactone 7-acetate, 7α-(Acetylthio)-17α-hydroxy-3-oxopregn-4-ene-21-carboxylic acid γ-lactone
• Formula empirica (notazione di Hill): C₂₄H₃₂O₄S
• Numero CAS: 52-01-7
• Peso molecolare: 416.57
• Numero MDL: MFCD00082250
• Codice UNSPSC: 41116107
• ID PubChem: 329751140
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: spironolactone
• Produttore/marchio commerciale: USP
• Punto di fusione: 207-208 °C (lit.)
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@]45CCC(=O)O5)[C@H]13
• InChI: 1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1; LXMSZDCAJNLERA-ZHYRCANASA-N
• Informazioni sul gene: human ... NR3C2(4306)

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Spironolactone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Spironolactone and Hydrochlorothiazide Compounded Oral Suspension
• Spironolactone and Hydrochlorothiazide Tablets
• Spironolactone Compounded Oral Suspension
• Spironolactone Compounded Oral Suspension, Veterinary
• Spironolactone Tablets

Azioni biochim/fisiol

Spironolactone is a competitive aldosterone receptor antagonist. Used as potassium sparing diuretic.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H351,H360FD,H373
• Consigli di prudenza: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Classi di pericolo: Carc. 2 - Repr. 1B - STOT RE 2
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable