T8453

Anti-β-Tubulin II antibody, Mouse monoclonal

clone 7B9, purified from hybridoma cell culture

• Sinonimo/i: Anti-TUBB2, Anti-Tubulin, β2
• Numero MDL: MFCD00145892
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Coniugato: unconjugated
• Forma dell’anticorpo: purified from hybridoma cell culture
• Tipo di anticorpo: primary antibodies
• Clone: 7B9, monoclonal
• Forma fisica: buffered aqueous solution
• PM: antigen ~50 kDa
• Reattività contro le specie: human, mouse, rat
• Concentrazione: ~1.0 mg/mL
• tecniche: immunocytochemistry: suitable; immunoprecipitation (IP): suitable; western blot: 1-2 μg/mL using Neuro-2a cell extract
• Isotipo: IgG1
• N° accesso UniProt: Q9BVA1
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... TUBB2B(347733) ; mouse ... Tubb2b(73710) ; rat ... Tubb2b(291081)

Descrizione

Descrizione generale

Monoclonal Anti- β-Tubulin II (mouse IgG1 isotype) is derived from the hybridoma 7B9 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to a fragment at the C-terminus of human β?tubulin II. Tubulin is the major building block of microtubules. This intracellular, cylindrical, filamentous structure is present in almost all eukaryotic cells. Tubulin is a heterodimer that consists of α-tubulin and β ?tubulin. Both subunits have a molecular mass of ~50 kDa and share considerable homology.

Applicazioni

Anti-β-Tubulin II antibody has been used in

• immunoblotting immunoprecipitation
• immunocytochemistry
• western blotting
• immunolabelling

Azioni biochim/fisiol

The αβ tubulins are involved in the formation of microtubules during cell division by the formation of protofilaments.

Stato fisico

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)