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Key Documents

T4512

Sigma-Aldrich

(±)-Taxifolin hydrate

≥90% (HPLC)

Sinonimo/i:

3,3′,4′,5,7-Pentahydroxyflavanone hydrate, Dihydroquercetin hydrate

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About This Item

Formula empirica (notazione di Hill):
C15H12O7 · xH2O
Numero CAS:
Peso molecolare:
304.25 (anhydrous basis)
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.25

Livello qualitativo

Saggio

≥90% (HPLC)

Forma fisica

powder

Solubilità

DMSO: 20 mg/mL

applicazioni

metabolomics
vitamins, nutraceuticals, and natural products

Temperatura di conservazione

−20°C

Stringa SMILE

O.O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3

InChI

1S/C15H12O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,14-19,21H;1H2/t14-,15+;/m0./s1
DNQPGSVMBPSRIR-LDXVYITESA-N

Informazioni sul gene

mouse ... Hexa(15211)

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Categorie correlate

Descrizione generale

Taxifolin or dihydroquercetin is a naturally occurring secondary metabolic compound found in many plants such as onions, milk thistle, Douglas fir bark, and French maritime pine bark.

Applicazioni

(±)-Taxifolin hydrate has been used to evaluate its effects when co-supplemented with trehalose to improve the quality of post-thawed ram semen. It may have been used as a reference standard to analyze the bioactive components of ethanolic extract of P. orientale (POE) using high-performance liquid chromatography (HPLC).

Azioni biochim/fisiol

(±)-Taxifolin exerts various pharmacological properties that include anti-inflammatory, anti-cancer, antiviral, and antimicrobial activities. It displays neuroprotective, hepatoprotective effects, and it also protects against cardiovascular diseases.
Flavonoid, antioxidant. Inhibits lipogenesis in cancer cells, most likely by targeting fatty acid synthase activity.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Sigma-Aldrich

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5-α-Cholestane

Isorhamnetin ≥95.0% (HPLC)

Sigma-Aldrich

17794

Isorhamnetin

(−)-Epicatechin analytical standard

Supelco

68097

(−)-Epicatechin

Yung-Jia Chiu et al.
Journal of food and drug analysis, 26(1), 369-379 (2018-02-02)
Polygonum orientale L. (Polygonaceae) fruits have various medicinal uses, but their hepatoprotective effects have not yet been studied. This study investigated the hepatoprotective activity of the ethanolic extract of P. orientale (POE) fruits against carbon tetrachloride (CCl4)-induced acute liver injury
Mustafa Numan Bucak et al.
Cryobiology, 96, 19-29 (2020-09-06)
This study aimed to evaluate the comparative effects of taxifolin hydrate and trehalose on the quality of frozen-thawed ram spermatozoa for the first time. Ejaculates collected from six mature rams were pooled, and divided to eight equal aliquots to extend

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