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Key Documents

T3705

Sigma-Aldrich

Transferrin human

Optiferrin™, recombinant, expressed in rice

Sinonimo/i:

Optiferrin™

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About This Item

Numero CAS:
11096-37-0
Numero CE:
234-318-8
Numero MDL:
MFCD00132442
Codice UNSPSC:
12352202
NACRES:
NA.61

Origine biologica

human

Ricombinante

expressed in rice

Saggio

≥95% (agarose gel electrophoresis)

Forma fisica

powder

Composizione

Protein, ≥90%

Tenore di ferro

≥300 μg/g

tecniche

immunoprecipitation (IP): suitable
tissue culture: suitable

Impurezze

≤1.0 EU/mg Endotoxin

N° accesso UniProt

P02787

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... TF(7018)

Descrizione generale

Transferrin is an 80 kDa serum glycoprotein, which is expressed in hepatocytes. The gene is located on human chromosome 3q22.1.
Optiferrin™ is recombinant human transferrin that is completelyblood-free. Optiferrin’s performance is equivalent to human holo transferrin incell culture and offers significant regulatory advantages due to its safety andconsistency. Optiferrin is suitable for a broad range of cell types thatinclude stem, primary, and bioproduction cells.

Applicazioni

Transferrin Human has been used to perform immunoprecipitation measurements. It has also been used for the preparation of essential 8 medium.

Azioni biochim/fisiol

Human transferrin was shown to promote allogeneic chimerism in mice after irradiation and transplantation of incompatible bone marrow.
Transferrin facilitates the transfer of iron to erythron and peripheral tissues. It stimulates the proliferation of human lymphocytes. Mutations in this gene are linked to atransferrinemia.

Altre note

1). Patent Rights
U.S. Patent No. 9,321,828
2). Registered Trademark Rights
U.S. Reg. 3,880,881
International Reg. 1,466,509

Note legali

Optiferrin is a trademark of InVitria

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Increasing serum transferrin to reduce tissue iron overload due to ineffective erythropoiesis
Tolosano E
The Hematology Journal : The Official Journal of the European Haematology Association / EHA (2015)
E Axelman et al.
Thrombosis and haemostasis, 112(3), 466-477 (2014-07-18)
Heparanase is implicated in cell invasion, tumour metastasis and angiogenesis. It forms a complex and enhances the activity of the blood coagulation initiator - tissue factor (TF). We describe new peptides derived from the solvent accessible surface of TF pathway
A remote-controlled immunochemical system for nephelometric detection of human serum transferrin
Strzelak K and Koncki R
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Effect of human transferrin on the engraftment of allogeneic bone marrow in various strans of lethally irradiated mice.
Pierpaoli W.
Nature Immunology, 11, 356-365 (1992)
Effect of transferrin, lactoferrin and chelated iron on human T-lymphocytes
Djeha A and Brock JH
British Journal of Haematology, 80(2), 235-241 (1992)
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