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T3516

Sigma-Aldrich

Thioflavin T

Powder

Sinonimo/i:

Basic Yellow 1, Thioflavine T

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About This Item

Formula empirica (notazione di Hill):
C17H19ClN2S
Numero CAS:
2390-54-7
Peso molecolare:
318.86
Colour Index:
49005
Beilstein:
3922452
Numero CE:
219-228-9
Numero MDL:
MFCD00011944
Codice UNSPSC:
12171500
ID PubChem:
24900146
NACRES:
NA.47

product name

Thioflavin T, used as stain for amyloid

Forma fisica

powder

Composizione

Dye content, ≥65%

Solubilità

methanol: 1 mg/mL

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

[Cl-].CN(C)c1ccc(cc1)-c2sc3cc(C)ccc3[n+]2C

InChI

1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
JADVWWSKYZXRGX-UHFFFAOYSA-M

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Categorie correlate

Descrizione generale

Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid. Thioflavin T has been used in histology and for protein characterization.

Applicazioni

Thioflavin T has been used to identify the presence of amyloid fibrils in samples.

Altre note

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Avvertenze

Danger

Indicazioni di pericolo

H301,H317,H318,H410

Classi di pericolo

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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G A Cornwall et al.
Andrology, 7(5), 603-609 (2019-01-22)
We previously demonstrated the normal mouse epididymal lumen contains a non-pathological amyloid matrix that surrounds spermatozoa and plays important roles in sperm maturation and protection. The objective herein was to present a review of this work, including studies showing the
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Biochimica et biophysica acta, 1804(7), 1405-1412 (2010-04-20)
Intense efforts to detect, diagnose, and analyze the kinetic and structural properties of amyloid fibrils have generated a powerful toolkit of amyloid-specific molecular probes. Since its first description in 1959, the fluorescent dye Thioflavin-T (ThT) has become among the most
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Biophysical chemistry, 220, 42-48 (2016-11-20)
The hydrophobic fragment of the Alzheimer's related β-amyloid (Aβ) peptide, Aβ(25-40), aggregates and forms insoluble amyloid fibrils at a rate similar to the full-length peptide. In order to gain insight into the fibrillization of Aβ(25-40) and the ability of the
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