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Key Documents

C6767

Sigma-Aldrich

Congo Red

Dye content ≥35 %, Powder

Sinonimo/i:

Congo Red 4B, Cosmos Red, Cotton Red B, Cotton Red C, Direct Red 28, Direct Red R, Direct Red Y

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About This Item

Formula empirica (notazione di Hill):
C32H22N6Na2O6S2
Numero CAS:
Peso molecolare:
696.66
Colour Index:
22120
Beilstein:
3894858
Numero CE:
Numero MDL:
Codice UNSPSC:
12171500
ID PubChem:
NACRES:
NA.47

product name

Congo Red, Dye content ≥35 %

Forma fisica

powder

Livello qualitativo

Composizione

Dye content, ≥35%

tecniche

titration: suitable

Colore

red-brown

pH

6.7 (10 g/L)

Punto di fusione

>360 °C (lit.)

Solubilità

H2O: 1 mg/mL

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

[Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c3ccc(cc3)-c4ccc(cc4)\N=N\c5cc(c6ccccc6c5N)S([O-])(=O)=O

InChI

1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;
IQFVPQOLBLOTPF-HKXUKFGYSA-L

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Applicazioni

  • Congo red has been used as a histochemical stain for the quantification of amyloid deposits in brain tissues.
  • It has been used as a cell wall inhibiting agent in fungus Cryptococcus neoformans.
  • It has also been used to study microstructural details in the cell walls of raw potato and fried potato using confocal microscopy.

Azioni biochim/fisiol

Congo red is a benzidine-based anionic diazo dye. It is a histological dye which binds to many amyloid proteins and is used for the quantification of amyloid β-peptide aggregation. Congo red also interacts with β-D-glucans, polysaccharides containing continuous β-(1→4)-linked D-glucopyranosyl units and some hemicellulosic galactoglucomannans.

Pittogrammi

Health hazard

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Carc. 1B - Repr. 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Sigma-Aldrich

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O A Odeyemi et al.
Microbial pathogenesis, 136, 103665-103665 (2019-08-14)
This study aimed to investigate antibiotic resistance and putative virulence factors among Cronobacter sakazakii isolated from powdered infant formula and other sources. The following 9 cultures (CR1-9) were collected from our culture collection: C. sakazakii and 3 Cronobacter species: C. sakazakii ATCC®
Some changes in potato chips during frying observed by confocal laser scanning microscopy (CLSM).
Pedreschi F and Aguilera JM
Food Science and Technology International = Ciencia y tecnologia de Los Alimentos Internacional, 8, 197-201 (2002)
Kinetic study and equilibrium isotherm analysis of Congo Red adsorption by clay materials.
Chemical Engineering Journal, 148, 354-364 (2009)
Quantification of cerebral amyloid angiopathy and parenchymal amyloid plaques with Congo red histochemical stain.
Wilcock DM, et al.
Nature Protocols, 1, 1591-1591 (2006)
PKC1 is essential for protection against both oxidative and nitrosative stresses, cell integrity, and normal manifestation of virulence factors in the pathogenic fungus Cryptococcus neoformans.
Gerik KJ, et al.
Eukaryotic Cell, 7, 1685-1685 (2008)

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