SML2966

Z-RLRGG-AMC Acetate

≥95% (HPLC)

• Sinonimo/i: N2-[(Phenylmethoxy)carbonyl]-L-arginyl-L-leucyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-glycinamide, Z-Arg-Leu-Arg-Gly-Gly-7-amido-4-methylcoumarin, Z-Arg-Leu-Arg-Gly-Gly-AMC
• Formula empirica (notazione di Hill): C₄₀H₅₆N₁₂O₉ · xC₂H₄O₂
• Numero CAS: 167698-69-3
• Peso molecolare: 848.95 (free base basis)
• Codice UNSPSC: 12352209
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95% (HPLC)
• Stato: film or powder
• Colore: white to beige
• Temperatura di conservazione: −20°C
• Stringa SMILE: FC(F)(F)C(=O)O.N([C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)NCC(=O)Nc2cc3c(cc2)C(=CC(=O)O3)C)C(=O)OCc1ccccc1
• InChI: 1S/C40H56N12O9.C2HF3O2/c1-23(2)17-30(51-36(57)29(12-8-16-46-39(43)44)52-40(59)60-22-25-9-5-4-6-10-25)37(58)50-28(11-7-15-45-38(41)42)35(56)48-20-32(53)47-21-33(54)49-26-13-14-27-24(3)18-34(55)61-31(27)19-26;3-2(4,5)1(6)7/h4-6,9-10,13-14,18-19,23,28-30H,7-; CMGDVBCGNGERLC-SZOHVZSOSA-N

Descrizione

Azioni biochim/fisiol

Z-RLRGG-AMC is a fluorogenic substrate for the MERS-CoV, SARS-CoV, SARS-CoV-2 papain-like protease (PLpros), deubiquitinating enzyme isopeptidase T (IPaseT) and other ubiquitin C-terminal hydrolases, which consists of the Ub and ISG15 C-terminal sequences. Z-RLRGG-AMC excitation wavelength is 340 nm, and emission wavelength is 460 nm.

fluorogenic substrate for the MERS-CoV, SARS-CoV, SARS-CoV-2 papain-like protease (PLpros), deubiquitinating enzyme isopeptidase T (IPaseT)

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable