SML1933
TP-472N
≥98% (HPLC)
Sinonimo/i:
1-[8-[2-(Cyclopropylmethoxy)phenyl]pyrrolo[1,2-a]pyrimidin-6-yl]-ethanone
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
About This Item
Formula empirica (notazione di Hill):
C19H18N2O2
Numero CAS:
Peso molecolare:
306.36
Numero MDL:
Codice UNSPSC:
12352200
Prodotti consigliati
Livello qualitativo
Saggio
≥98% (HPLC)
Forma fisica
powder
Colore
white to beige
Solubilità
DMSO: 15 mg/mL, clear
Temperatura di conservazione
2-8°C
Stringa SMILE
O=C(C)C1=CC(C2=CC=CC=C2OCC3CC3)=C4N=CC=CN41
Categorie correlate
Azioni biochim/fisiol
TP-472N is a negative control probe for TP-472. TP-472 is a selective probe for bromodomain-containing proteins BRD9 and BRD7. The BRD9/7 probe was developed out of a collaborative effort by Takeda and the SGC, and is of a different chemotype from BRD9/7 probes previously available. TP-472 has a KD value of 33nM for BRD9 and 340nM for BRD7 by ITC, is >30 fold selective for BRD9 over all other bromodomain family members except BRD7, and is suitable for in vivo applications. The negative control TP-472N is inactive against other bromodomains (>20μM against BRD9). For full characterization details of TP-472 and TP-472N, please visit the TP-472 probe summary on the Structural Genomics Consortium (SGC) website.
TP-472, the active BRD9/7 probe, is available from Sigma. To learn more about and purchase TP-472, click here.
To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
TP-472, the active BRD9/7 probe, is available from Sigma. To learn more about and purchase TP-472, click here.
To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
Caratteristiche e vantaggi
TP-472N is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.