SML0804

(S)-CPP sodium salt

≥96% (HPLC)

• Sinonimo/i: (S)-2-Chloro-3-phenylpropanoic acid sodium salt, (aS)-a-chloro-benzenepropanoic acid sodium salt
• Formula empirica (notazione di Hill): C₉H₈ClO₂ · Na
• Numero CAS: 194979-70-9
• Peso molecolare: 206.60
• Numero MDL: MFCD28118980
• Codice UNSPSC: 12352200
• ID PubChem: 329825602
• NACRES: NA.77

Proprietà

• Saggio: ≥96% (HPLC)
• Stato: powder
• Colore: white to beige
• Solubilità: H₂O: 20 mg/mL, clear
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: [O-]C([C@@H](Cl)CC1=CC=CC=C1)=O.[Na+]
• InChI: 1S/C9H9ClO2.Na/c10-8(9(11)12)6-7-4-2-1-3-5-7;/h1-5,8H,6H2,(H,11,12);/q;+1/p-1/t8-;/m0./s1; HMHPCHNNVOLTFC-QRPNPIFTSA-M

Descrizione

Azioni biochim/fisiol

(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase.

(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase. BDK is a negative regulator of BCKDC activity. Inhibition of BDK by (S)-CPP (IC₅₀ = 6.3 μM) leads to complex activation, and significant reduction of plasma levels of leucine/isoleucine and valine in wild type mice.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable