SCP0046
Amyloid β 28-35 human
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About This Item
Formula empirica (notazione di Hill):
C36H67N9O9S1
Peso molecolare:
802.04
Codice UNSPSC:
12352200
NACRES:
NA.32
Prodotti consigliati
![[Ala28]-Amyloid β 25-35 ≥95% (HPLC)](/deepweb/assets/sigmaaldrich/product/images/306/938/dd9f7c72-cfca-4ea3-8e10-a7a2a7994639/640/dd9f7c72-cfca-4ea3-8e10-a7a2a7994639.jpg)
![[Gln22]-Amyloid β 1-40 human ≥95% (HPLC)](/deepweb/assets/sigmaaldrich/product/images/707/874/59f84b84-17c2-494f-b2ae-4ca860b83976/640/59f84b84-17c2-494f-b2ae-4ca860b83976.jpg)
Saggio
≥95% (HPLC)
Stato
lyophilized
Composizione
Peptide Content, ≥75%
Condizioni di stoccaggio
protect from light
Temperatura di conservazione
−20°C
Amino Acid Sequence
Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met
Applicazioni
Amyloid β (Aβ) refers to peptides derived from Amyloid precursor protein that vary in length from 36-43 amino acids. Aβ(s) peptides, their peptide fragments and mutated fragments are used to study a wide range of metabolic and regulatory functions including activation of kinases, regulation of cholesterol transport, function as a transcription factor, and regulators of inflammation. Aβ(s) peptides and their peptide fragments are also used to study oxidative stress, metal binding and mechanisms of protein cross-linking in the context of diseases such as Alzheimer′s disease and neurodegeneration.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Sureshbabu Nagarajan et al.
The FEBS journal, 275(10), 2415-2427 (2008-04-22)
The interaction of the beta-amyloid peptide (Abeta) with neuronal membranes could play a key role in the pathogenesis of Alzheimer's disease. Recent studies have focused on the interactions of Abeta oligomers to explain the neuronal toxicity accompanying Alzheimer's disease. In
Sureshbabu Nagarajan et al.
Journal of structural biology, 170(3), 439-450 (2010-03-02)
Folding and self-assembly of amyloid beta (Abeta) peptide are linked to Alzheimer's disease. To understand the initial stage of amyloid-beta peptide aggregation, conformational characteristics of monomers of wild-type (WT) Abeta(28-35) and its mutant peptides A30G and A30I were investigated using
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