SAB4503879

Anti-phospho-HSL (pSer⁵⁵²) antibody produced in rabbit

affinity isolated antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen 116 kDa
• Reattività contro le specie: mouse, rat, human
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:5000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• N° accesso NCBI: Q05469
• N° accesso UniProt: Q05469
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pSer552)
• Informazioni sul gene: human ... LIPE(3991)

Descrizione

Descrizione generale

Hormone sensitive lipase (HSL) is coded by LIPE (lipase E) gene. It is an intracellular lipase with substrates as triglycerides, diglycerides, monoglycerides, cholesterol esters and retinyl esters. HSL is mapped to human chromosome 19q13.

Immunogeno

The antiserum was produced against synthesized peptide derived from human HSL around the phosphorylation site of Ser552.

Immunogen Range: 518-567

Applicazioni

Anti-HSL antibody has been used in western blotting.

Azioni biochim/fisiol

Hormone sensitive lipase (HSL) plays an important role in lipolysis. Lack of HSL results in histologic abnormalities in white adipose tissue and an increase in macrophage infiltration.

Caratteristiche e vantaggi

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Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable