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Merck
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SAB4503057

Sigma-Aldrich

Anti-PGP9.5 antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

UCH-L1, neuron cytoplasmic protein 9.5, ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin thiolesterase L1

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

antigen 24 kDa

Reattività contro le specie

mouse, rat, human

Concentrazione

~1 mg/mL

tecniche

ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

N° accesso UniProt

P09936

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... UCHL1(7345)

Descrizione generale

Anti-PGP9.5 Antibody detects endogenous levels of total PGP9.5 protein.
The PGP9.5 (protein gene product 9.5) gene is mapped to human chromosome 4p13. The encoded protein is predominantly expressed in the brain.

Immunogeno

The antiserum was produced against synthesized peptide derived from human PGP9.5.

Immunogen Range: 171-220

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Manasi Sayilekshmy et al.
Scientific reports, 9(1), 5361-5361 (2019-03-31)
Mounting evidence from animal studies suggests a role of the nervous system in bone physiology. However, little is known about the nerve fiber localization to human bone compartments and bone surface events. This study reveals the density and distribution of
Iris Shinkarevsky Fleitman et al.
Muscle & nerve, 61(6), 791-796 (2020-03-07)
Small-fiber neuropathy is rare in children. It has been associated with several autoimmune disorders, but there are no reports of an autoinflammatory etiology. The data of four children/adolescents presenting with erythromelalgia and neuropathic pain from 2014 to 2019 were collected
Mitochondria: The Next (Neurode)Generation
Schon EA, et al.
Neuron, 70(6), 1033-1053 (2011)
Familial Mutations and Post-translational Modifications of UCH-L1 in Parkinson's Disease and Neurodegenerative Disorders.
C Lee YT, et al.
Current Protein and Peptide Science, 18(7), 733-745 (2017)
Rie B Hansen et al.
Frontiers in pain research (Lausanne, Switzerland), 3, 887747-887747 (2022-06-18)
Pain is a common complication for patients with metastatic bone disease. Animal models suggest that the pain, in part, is driven by pathological sprouting and reorganization of the nerve fibers innervating the bone. Here, we investigate how these findings translate
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