SAB4502260

Anti-PPAR-α antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: NR1C1, PPAR-α, PPARA Peroxisome proliferator-activated receptor α
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen 52 kDa
• Reattività contro le specie: human, rat, mouse
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:1000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• N° accesso NCBI: Q07869
• N° accesso UniProt: Q07869
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... PPARA(5465)

Descrizione

Descrizione generale

Anti-PPAR-α antibody detects endogenous levels of total PPAR-α protein.

The PPAR-α (peroxisome proliferator-activated receptor α) gene is mapped to human chromosome 22q13.31. Ppar-α is localized to the nucleus.

Immunogeno

The antiserum was produced against synthesized peptide derived from human PPAR-alpha.

Immunogen Range: 6-55

Azioni biochim/fisiol

PPAR-α (peroxisome proliferator-activated receptor α) is a receptor transcription factor that inhibits inflammation, by preventing the nuclear factor κB activation. Omega-3 long-chain polyunsaturated fatty acids is known to be the ligand that brings out the anti-inflammatory action of Ppar-α. Ppar-α is involved in epidermal proliferation and differentiation and therefore serves as a skin barrier. PPARα mediates lipid metabolism by inducing fatty acid oxidation and also regulates glucose metabolism. Variation in the gene is observed in schizophrenia.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable