Passa al contenuto
Merck
Tutte le immagini(2)

Documenti

SAB4502234

Sigma-Aldrich

Anti-Cytochrome c antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

CYC, CYCS, Cytochrome c

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(2)

About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

antigen 11 kDa

Reattività contro le specie

human, rat, mouse

Concentrazione

~1 mg/mL

tecniche

ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

N° accesso NCBI

P99999

N° accesso UniProt

P99999

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... CYCS(54205)

Descrizione generale

Anti-Cytochrome c antibody detects endogenous levels of total Cytochrome c protein.
The cytochrome c gene is mapped to human chromosome 7p15.3. The encoded protein consists of two thioether present between heme and two cysteine residues included in a CXXCH motif (highly conserved). It is localized to mitochondrial intermembrane space.

Immunogeno

The antiserum was produced against synthesized peptide derived from human Cytochrome c.

Immunogen Range: 10-59

Applicazioni

Anti-Cytochrome c, N-terminal antibody produced in rabbit has been used in western blot analysis.

Azioni biochim/fisiol

Cytochrome c is a water-soluble intermediary of electron transport chain. It acts as an ROS (reactive oxygen species) scavenger, and involved in redox-mediated protein import and apoptosis. Cytochrome c has peroxidase activity, contributing towards intrinsic pathway of apoptosis.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Motore di ricerca dei prodotti.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 1

1 of 1

N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin ≥95% (HPLC), powder

Sigma-Aldrich

A5845

N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin

Erez Eitan et al.
Cerebellum (London, England), 15(4), 509-517 (2015-09-17)
Telomerase reverse transcriptase (TERT) is the catalytic subunit of telomerase, an enzyme that elongates telomeres at the ends of chromosomes during DNA replication. Recently, it was shown that TERT has additional roles in cell survival, mitochondrial function, DNA repair, and
Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis.
Jiang X
Proceedings of the National Academy of Sciences of the USA, 111(41), 14782-14787 (2014)
Apobec2 deficiency causes mitochondrial defects and mitophagy in skeletal muscle.
Sato Y
Faseb Journal (2017)
Evaluation of the adaptogenic potential exerted by ginsenosides Rb1 and Rg1 against oxidative stress-mediated neurotoxicity in an in vitro neuronal model.
Fernandez-Moriano C
PLoS ONE, 12(8), 1-22 (2017)
Effect of a K72A Mutation on the Structure, Stability, Dynamics, and Peroxidase Activity of Human Cytochrome c.
Nold SM
Biochemistry, 56(26), 3358-3368 (2017)
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.