SAB4501949
Anti-MYPT1 antibody produced in rabbit
affinity isolated antibody
Sinonimo/i:
MBS, Myosin phosphatase target subunit 1, PPP1R12A
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About This Item
Prodotti consigliati
Origine biologica
rabbit
Coniugato
unconjugated
Forma dell’anticorpo
affinity isolated antibody
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Forma fisica
buffered aqueous solution
PM
antigen 115 kDa
Reattività contro le specie
human, mouse, rat
Concentrazione
~1 mg/mL
tecniche
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
wet ice
Temperatura di conservazione
−20°C
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... PPP1R12A(4659)
Categorie correlate
Descrizione generale
Anti-MYPT1 Antibody detects endogenous levels of total MYPT1 protein. Myosin phosphatase target subunit 1 (MYPT1) is also known as protein phosphatase 1 regulatory subunit 12A (PPP1R12A). It is the regulatory subunit of the myosin light chain phosphatase. MYPT1 has a molecular weight of 130 kDa. The gene encoding this protein is localized on human chromosome 12q21.2.
Immunogeno
The antiserum was produced against synthesized peptide derived from human MYPT1.
Immunogen Range: 621-670
Immunogen Range: 621-670
Azioni biochim/fisiol
Myosin phosphatase target subunit 1 (MYPT1) has a role in the modulation of the myosin light chain phosphatase through its multiple phosphorylation sites. It aids in the interaction of protein phosphatase-1 catalytic subunit δ (PP1C) with myosin filaments. MYPT1 acts as an antagonist of polo-like kinase-1 (PLK1) and has a role in regulating mitosis.
Caratteristiche e vantaggi
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Stato fisico
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
nwg
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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