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Merck
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Documenti fondamentali

SAB4301578

Sigma-Aldrich

Anti-phospho-ERK1/2 (pThr202/Tyr204) antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

ERK-1, ERK1, ERT2, P44ERK1, PRKM3

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

PM

42 kDa
 44 kDa

Reattività contro le specie

rat, mouse, human

Concentrazione

1.0 mg/mL

tecniche

western blot: 1:500-1:1000 (Cell Lysate)

Isotipo

IgG

Numero d’accesso

NP_001035145.1 

N° accesso UniProt

P27361

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

phosphorylation (pThr202/pTyr204)

Informazioni sul gene

human ... MAPK3(5595)

Specificità

The antibody detects endogenous level of p44/42 MAP Kinase only when phosphorylated at Threonine 202 and Tyrosine 204 .

Immunogeno

Peptide sequence around phosphorylation site of Threonine 202/Tyrosine 204(F-L-T(p)-E-Y(p)-V-A) derived from Human p44/42 MAP Kinase.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
461212082

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Vittorio Perfetti et al.
Oncotarget, 8(34), 56158-56167 (2017-09-17)
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. GISTs express the receptor tyrosine kinase KIT, and the majority of GISTs present KIT gain-of-function mutations that cluster in the 5' end of the receptor juxtamembrane
Varun Kumar et al.
Current eye research, 46(5), 710-718 (2020-10-28)
Understanding molecular changes is essential for designing effective treatments for nonarteritic anterior ischemic optic neuropathy (AION), the most common acute optic neuropathy in adults older than 50 years. We investigated changes in the mitogen-activated protein kinase (MAPK) pathway after experimental AION
Ravinder K Goyal et al.
BMC genomics, 19(1), 178-178 (2018-03-07)
The mitogen-activated protein kinase (MAPK) family is involved in signal transduction networks that underpin many different biological processes in plants, ranging from development to biotic and abiotic stress responses. To date this class of enzymes has received little attention in
Lenka Halova et al.
Open biology, 11(4), 200405-200405 (2021-04-08)
Fluctuations in TOR, AMPK and MAP-kinase signalling maintain cellular homeostasis and coordinate growth and division with environmental context. We have applied quantitative, SILAC mass spectrometry to map TOR and nutrient-controlled signalling in the fission yeast Schizosaccharomyces pombe. Phosphorylation levels at
Yuhang Yuan et al.
Cell cycle (Georgetown, Tex.), 17(11), 1390-1402 (2018-06-29)
Necrotizing enterocolitis (NEC) is a potentially fatal illness in premature neonates. Tumor necrosis factor-α (TNF-α) and autophagy are associated with the pathogenesis of NEC. This study aimed to explore whether TNF-α might regulate apoptosis in neonatal NEC model cells IEC-6
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