SAB3501228

Anti-Avian Influenza A M2 antibody produced in rabbit

affinity isolated antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: liquid
• Reattività contro le specie: influenza A virus (avian)
• Concentrazione: 1 mg/mL
• tecniche: ELISA: suitable
• Isotipo: IgG
• N° accesso UniProt: Q2L7I8
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified

Descrizione

Descrizione generale

Avian Influenza A M2 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however, it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in Southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. The influenza membrane ion channel (M2) is a small transmembrane protein that regulates the pH inside the virion during viral entry into the cell and protects the newly synthesized hemagglutinin during their transport through low pH cellular compartments. It has been suggested as a target of neutralizing antibodies.

Immunogeno

M2 antibody was raised against a 13 amino acid synthetic peptide from amino terminus of H5N1 M2.The immunogen is located within the first 50 amino acids of Avian Influenza A M2.

Applicazioni

M2 antibody can be used for the detection of the M2 protein from the H5N1 strain of avian influenza A in ELISA. It will detect 10 ng of free peptide at 1 mg/mL.

Stato fisico

Supplied in PBS containing 0.02% sodium azide.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable