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Documenti fondamentali

SAB2501669

Sigma-Aldrich

Anti-CASP3 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

HGNC:1504, caspase 3, caspase 3, apoptosis-related cysteine peptidase, caspase 3, apoptosis-related cysteine protease

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

goat

Livello qualitativo

100

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

Reattività contro le specie

canine, mouse, human, rat

tecniche

indirect ELISA: suitable
western blot: suitable

N° accesso UniProt

P42574

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... CASP3(836)

Immunogeno

Peptide with sequence C-RDVSKEDHSKRS, from the internal region of the protein sequence according toNP_004337.2; NP_116786.1

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

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Raccomandato

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
7286P1

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Wan Wang et al.
Journal of controlled release : official journal of the Controlled Release Society, 191, 4-14 (2014-05-02)
αB-Crystallin is a protein chaperone with anti-apoptotic and anti-inflammatory activity that is apically secreted in exosomes by polarized human retinal pigment epithelium. A 20 amino acid mini-peptide derived from residues 73-92 of αB-crystallin protects human retinal pigment epithelial (RPE) cells
Laura Masuelli et al.
Journal of translational medicine, 12, 122-122 (2014-06-03)
The antitumor activity induced by intratumoral vaccination with poxvirus expressing a tumor antigen was shown to be superior to that induced by subcutaneous vaccination. Salivary gland carcinomas overexpress ErbB2. Trastuzumab, a monoclonal antibody to ErbB2, was proposed for salivary gland
Jia-Ren Liu et al.
Shock (Augusta, Ga.), 42(6), 532-539 (2014-07-31)
Macrophage 1 antigen (Mac-1, CD11bCD18) is a leukocyte adhesion molecule that is involved in many functions including leukocyte recruitment, phagocytosis, and neutrophil apoptosis. The previous report of mild polymicrobial, abdominal sepsis showed that the administration of anti-CD11b-blocking antibody administration attenuated
Lars Vereecke et al.
Nature communications, 5, 5103-5103 (2014-10-01)
The transcription factor NF-κB is indispensable for intestinal immune homeostasis, but contributes to chronic inflammation and inflammatory bowel disease (IBD). A20, an inhibitor of both NF-κB and apoptotic signalling, was identified as a susceptibility gene for multiple inflammatory diseases, including
Kevin Hollevoet et al.
Molecular cancer therapeutics, 13(8), 2040-2049 (2014-06-15)
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, and new therapies are needed. RG7787 is a novel low-immunogenic antimesothelin recombinant immunotoxin (RIT), engineered to overcome the limitations of SS1P, a RIT now in clinical trials. In vitro activity was evaluated
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