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Key Documents

S9399

Sigma-Aldrich

Staphylococcal enterotoxin A from Staphylococcus aureus

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About This Item

Numero CAS:
642595-84-4
Numero MDL:
MFCD00082015
Codice UNSPSC:
12352200

contiene

sodium phosphate buffer as balance

Livello qualitativo

200

Composizione

Protein, ~10% Lowry

Disponibilità

not available in USA

Impurezze

Staphylococcal enterotoxin B (SEB), essentially free

Solubilità

H2O: complete 1 mg/ml, clear, colorless

Temperatura di conservazione

2-8°C

Descrizione generale

Staphylococcal enterotoxin A belongs to the family of staphylococcal exotoxins. It is secreted by Staphylococcus aureus, a Gram-positive bacteria.

Applicazioni

Staphylococcal enterotoxin A from Staphylococcal aureus was injected peritoneally in mice to induce sepsis.10
Staphylococcal enterotoxin A from Staphylococcus aureus has been used as an external standard in for the verification of TRANSIA assay kit, RIDASCREEN assay kit and Vidas Set 2 method. For in vitro toxin stimulation of mouse splenocytes.

Azioni biochim/fisiol

Staphylococcal enterotoxin A from Staphylococcus aureus is leading agent that causes of food poisoning. A concentration of as little as 0.5 mg/ml is sufficient to result in nausea, vomiting, diarrhea and cramps.8 It stimulates the cell proliferation of peripheral lymphocytes, induces the production of interferons and is important for gut immunity against S. aureus infections.9 It acts as a super antigen for T-lymphocytes.

Confezionamento

Package size based on protein content

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302 + H332

Classi di pericolo

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Codice della classe di stoccaggio

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

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Hongshi Yu et al.
BMC genomics, 10, 416-416 (2009-09-08)
WNT4 is a critical signalling molecule in embryogenesis and homeostasis, but the elements that control its transcriptional regulation are largely unknown. This study uses comparative cross species sequence and functional analyses between humans and a marsupial (the tammar wallaby,Macropus eugenii)
Staphylococcal enterotoxin A (SEA).
L Spero et al.
Methods in enzymology, 78(Pt A), 331-336 (1981-01-01)
Targeting of key pathogenic factors from gram-positive bacteria by the soluble ectodomain of the scavenger-like lymphocyte receptor CD6
<BIG>Martinez F, et al.</BIG>
The Journal of Infectious Diseases, 209, 1077-1086 (2013)
Marcin Kłak et al.
Scandinavian journal of infectious diseases, 42(5), 351-358 (2010-01-27)
Haemostatic balance shifts towards pro-coagulation during infection. Plasminogen, a key molecule of fibrinolysis, may play an important role in the pathogenesis of staphylococcal infections. In the present study, we assessed the impact of inhibition of plasminogen activation by tranexamic acid
Staphylococcal Enterotoxins
<BIG>Pinchuk IV, et al.</BIG>
Toxins, 2, 2177-2177 (2010)
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