P7556

Progesterone-Water Soluble

powder, BioReagent, suitable for cell culture

• Sinonimo/i: Progesterone: HBC complex, Progesterone: methyl-β-cyclodextrin complex
• Numero MDL: MFCD00003658
• Codice UNSPSC: 12352209
• ID PubChem: 57654558
• NACRES: NA.77

Proprietà

• Origine biologica: synthetic (organic)
• Nome Commerciale: BioReagent
• Saggio: ≥65% (HPLC)
• Stato: powder
• Concentrazione: ≥65% (HPLC)
• tecniche: cell culture | mammalian: suitable
• Solubilità: H₂O: 25 mg/mL, clear to slightly hazy
• Condizioni di spedizione: ambient
• Temperatura di conservazione: room temp
• Stringa SMILE: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(C)=O
• InChI: 1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1; RJKFOVLPORLFTN-LEKSSAKUSA-N
• Informazioni sul gene: human ... ABCB1(5243) , AR(367) , CYP2C9(1559) , EBP(10682) , ESR1(2099) , ESR2(2100) , NR3C1(2908) , NR3C2(4306) , PGR(5241) , SERPINA6(866) ; mouse ... Esr1(13982) ; rat ... Ar(24208) , Nr3c1(24413) , Pgr(25154)

Descrizione

Descrizione generale

Progesterone is a steroid hormone secreted by the ovaries.

Applicazioni

Progesterone-Water Soluble has been used:

• for in vitro maturation of oocyte complexes
• as a σ1R antagonist to study its effect on sigma 1 receptor
• to study its effect on the differentiation of human multipotent mesenchymal stromal cells (hMSCs) in vitro

This product is not recommended for use in binding assays.

Azioni biochim/fisiol

Progesterone is a hormone that maintains pregnancy. It is essential for embryo formation, development and survival in almost all mammals. This hormone exhibits its action via progesterone receptor, which is specifically expressed in the endometrial stroma throughout pregnancy. It is known to prevent preterm delivery, when administered intramuscularly. Progesterone also controls gonadotropin secretion, activates sexual behavior and triggers ovarian events leading to ovulation. It stimulates the growth and differentiation of the uterus and prevents uterine contractility.

Confezionamento

Package size based on progesterone content

Altre note

Contains approx. 70 mg progesterone per gram; balance methyl-β-cyclodextrin.

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H351,H360FD,H362
• Consigli di prudenza: P202 - P260 - P263 - P264 - P280 - P308 + P313
• Classi di pericolo: Carc. 2 - Lact. - Repr. 1A
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable