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P4638

Sigma-Aldrich

Poli-L-ornitina

suitable for cell culture, Mol wt >100,000

Sinonimo/i:

L-Ornithine homopolymer hydrobromide

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About This Item

Numero CAS:
27378-49-0
Numero MDL:
MFCD00237231
Codice UNSPSC:
12352209
NACRES:
NA.26

product name

Poli-L-ornitina, mol wt >100,000

Forma fisica

powder

PM

>100,000

tecniche

cell culture | mammalian: suitable

Colore

white to off-white

Temperatura di conservazione

−20°C

InChI

1S/C5H12N2O2.BrH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H
GWRQMKDBBHFVIZ-UHFFFAOYSA-N

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Applicazioni


  • Thermodynamic Characterization of Polypeptide Complex Coacervation.: The research investigates the thermodynamic properties of polypeptide complex coacervation, including the role of Poly-L-ornithine hydrobromide in these interactions. This study provides insights into the self-assembly processes of polypeptides, which are crucial for designing new biomaterials (Priftis et al., 2012).

Risultati analitici

Molecular weight based on viscosity.

Altre note

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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E Ramsay et al.
International journal of pharmaceutics, 210(1-2), 97-107 (2001-02-13)
The impetus to develop non-viral gene delivery vectors has led to examination of synthetic polycationic polymers as plasmid DNA (pDNA) condensing agents. Previous reports have highlighted superiority (up to x 10-fold) in the in-vitro transfection of pDNA complexes formed by
Omaditya Khanna et al.
Journal of biomedical materials research. Part A, 95(2), 632-640 (2010-08-21)
Alginate microcapsules coated with a permselective poly-L-ornithine (PLO) membrane have been investigated for the encapsulation and transplantation of islets as a treatment for type 1 diabetes. The therapeutic potential of this approach could be improved through local stimulation of microvascular
Ana Borrajo et al.
Neuropharmacology, 85, 1-8 (2014-06-01)
Several recent studies have shown that activation of the RhoA/Rho-associated kinase (ROCK) pathway is involved in the MPTP-induced dopaminergic cell degeneration and possibly in Parkinson's disease. ROCK inhibitors have been suggested as candidate neuroprotective drugs for Parkinson's disease. However, the
E Ramsay et al.
Journal of drug targeting, 10(1), 1-9 (2002-05-09)
Gene transfer vectors formed between the cationic polyamino acid, poly-(L)-omithine (PLO) and plasmid DNA (pDNA) have demonstrated superior transfection efficiency (up to x 10-fold) compared to equivalent polylysine-based systems in-vitro. The mechanism(s) underlying this observation remains to be elucidated. We
S K Tam et al.
Acta biomaterialia, 7(4), 1683-1692 (2010-12-15)
There is a need for better understanding of the biocompatibility of alginate-polycation microcapsules based on their physicochemical characteristics. Microcapsules composed of alginate with 44% (IntG) or 71% (HiG) guluronate, gelled with calcium (Ca) or barium (Ba) and coated with poly-L-lysine
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