P4509

Palmitoyl-DL-carnitine chloride

powder

• Sinonimo/i: DL-Hexadecanoylcarnitine, Hexadecanoyl-DL-carnitine, NSC 628323, ​DL-Palmitoylcarnitine
• Formula condensata: C₂₃H₄₆NO₄ · Cl
• Numero CAS: 6865-14-1
• Peso molecolare: 436.07
• Numero MDL: MFCD00063481
• Codice UNSPSC: 12352200
• ID PubChem: 24278634
• NACRES: NA.77

Proprietà

• Origine biologica: synthetic (organic)
• Saggio: ≥98% (TLC)
• Forma fisica: powder
• Colore: white
• Solubilità: H₂O: 25 mg/mL (with heat or sonication)
• Temperatura di conservazione: −20°C
• Stringa SMILE: Cl.CCCCCCCCCCCCCCCC(=O)OC(CC(O)=O)C[N](C)(C)C
• InChI: 1S/C23H46NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4;/h21H,5-20H2,1-4H3,(H,25,26);1H; LGVBWSFTXDIBPB-UHFFFAOYSA-N

Descrizione

Applicazioni

Palmitoyl-DL-carnitine chloride has been used to study its effect on inflammatory cytokines and calcium (Ca²⁺) influx, using in vitro models of prostate cancer.

Azioni biochim/fisiol

Long-chain acylcarnitine and well-known intermediate in mitochondrial fatty acid oxidation. Modifies myocardial levels of high-energy phosphates and free fatty acids in the heart. Increases erythroid colony formation in culture. Reduces surface negative charge of erythrocytes and myocytes. Reported to affect currents and inhibit endothelium-dependent relaxation induced by acetylcholine and substance P in a dose dependent manner by suppressing the intracellular calcium signal transduction in endothelial cells.

Palmitoyl-DL-carnitine chloride is known to inhibit biofilm formation mediated by Pseudomonas aeruginosa and Escherichia coli. It is a phosphokinase C inhibitor.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)