Passa al contenuto
Merck
Tutte le immagini(3)

Key Documents

Altri documenti

O6503

Sigma-Aldrich

L-Ornithine monohydrochloride

BioReagent, suitable for cell culture, ≥99%

Sinonimo/i:

(S)-2,5-Diaminopentanoic acid monohydrochloride

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(3)

About This Item

Formula empirica (notazione di Hill):
C5H12N2O2 · HCl
Numero CAS:
3184-13-2
Peso molecolare:
168.62
Beilstein:
3625847
Numero CE:
221-678-6
Numero MDL:
MFCD00064562
Codice UNSPSC:
12352209
ID PubChem:
24898036
NACRES:
NA.75

Origine biologica

microbial

Nome Commerciale

BioReagent

Saggio

≥99%

Forma fisica

powder

Confezionamento

pkg of 100 g
pkg of 25 g

tecniche

cell culture | mammalian: suitable

Impurezze

ammonia and citrulline, essentially free

Solubilità

H2O: soluble 50 mg/mL, clear, colorless to very faintly yellow

Stringa SMILE

Cl.NCCC[C@H](N)C(O)=O

InChI

1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1
GGTYBZJRPHEQDG-WCCKRBBISA-N

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

L-Ornithine is the functional metabolite of L-arginine.
L-Ornithine is an amino acid that is not coded for by the genetic code. It is formed during the decomposition of argininine by arginase and participates in the urea cycle. Ornithine is the starting point for the formation of a family of polyamines that include spermine, spermidine and putrescine.

Applicazioni

L-Ornithine monohydrochloride has been used:
  • as a supplement in Dulbecco′s modified eagle medium (DMEM) for cell growth assays
  • as a component in the standard medium for primary human hepatocytes (PHH) culture
  • as a creatine synthesis inhibitor

Azioni biochim/fisiol

L-ornithine acts as a precursor for polyamines. It may modulate the intake of food as an acute satiety signal in the neonatal chick brain.
L-Ornithine is used as a media supplement to support the biosynthesis of polyamines.

Altre note

Product of arginine degradation by arginase

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 5

1 of 5

Putrescine dihydrochloride powder, BioReagent, suitable for cell culture

Sigma-Aldrich

P5780

Putrescine dihydrochloride

D-Ornithine monohydrochloride ~98%

Sigma-Aldrich

O5250

D-Ornithine monohydrochloride

L-arginina from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

A8094

L-arginina

Sigma-Aldrich

Sigma-Aldrich

869001-M

Follicle Stimulating Hormone, Human Pituitary, Iodination Grade

L-prolina from non-animal source, meets EP, USP testing specifications, suitable for cell culture

Sigma-Aldrich

P5607

L-prolina

Z N Canellakis et al.
The Yale journal of biology and medicine, 62(5), 481-491 (1989-09-01)
The polyamines and their derivatives are essential for life in eukaryotic and most prokaryotic cells, but their exact role in preserving cell function is not clear. These polyamines provide endogenous cations and thus participate in regulation of the intracellular pH;
Arginase 2 suppresses renal carcinoma progression via biosynthetic cofactor pyridoxal phosphate depletion and increased polyamine toxicity
Ochocki JD, et al.
Cell Metabolism, 27(6), 1263-1280 (2018)
Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
Ji L, et al.
Immunity, 51(2), 272-284 (2019)
Arginine
Profiles of Drug Substances, Excipients, and Related Methodology, 27, 1-32 (2001)
L-Ornithine is a potential acute satiety signal in the brain of neonatal chicks
Tran PV, et al.
Physiology & Behavior, 155, 141-148 (2016)
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.