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Merck
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Documenti fondamentali

MAK127

Sigma-Aldrich

Copper Assay Kit

sufficient for 250 colorimetric tests

Sinonimo/i:

Copper Test Kit

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About This Item

Codice UNSPSC:
12161503
NACRES:
NA.84

impiego

sufficient for 250 colorimetric tests

Metodo di rivelazione

colorimetric

Malattie correlate

orthopedic diseases; aging/geriatric diseases; hematological disorder; gastrointestinal diseases; neurological disorders; dermatological diseases

Temperatura di conservazione

2-8°C

Categorie correlate

Descrizione generale

Copper is an essential trace element. Copper-containing enzymes play important roles in iron and catecholamine metabolism, free radical scavenging, and in the synthesis of hemoglobin, elastin, and collagen. Copper is mainly present in ceruloplasmin in the liver. Low levels of copper have been associated with mental retardation, depigmentation, anemia, hypotonia, and scorbutic changes in bone. Levels of copper are key diagnostic indicator of diseases such as Wilson′s disease, microcytic hypochromic anemia, and bone disease due to reduced collagen synthesis.

Applicazioni

Copper Assay Kit has been used to determine the copper content colorimetrically in samples.

Caratteristiche e vantaggi

Compatible with high-throughput handling systems. Can be adapted for use with cuvettes.

Compatibilità

Suitable for the detection of of copper in biological, environmental, food, and beverage samples. Suitable for studying the effects of compounds on copper metabolism.

Principio

The method utilizes a chromogen that forms a colored complex specifically with copper ions. The intensity of the color, measured colorimetrically (359 nm), is directly proportional to copper concentration in the sample. The range of linear detection is 7 μg/dL (1.0 μM) to 300 μg/dL (47 μM).

Avvertenze

Danger

Indicazioni di pericolo

H290,H314,H335,H410

Classi di pericolo

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

8B - Non-combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
127CC01A04
127CB06A16
127CB07A16
127CA10A02
127CA01A23

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Estimating global enzyme abundance levels from cofactor requirements: a model-based analysis of the iron metabolism in yeast.
Dikicioglu D and Oliver SG
bioRxiv, 229104-229104 (2017)
Gabriela Fernandes et al.
The journal of adhesive dentistry, 22(3), 265-274 (2020-05-22)
To investigate whether dental adhesives modified with polyacrylic acid copper iodide particles could inhibit esterase activity in vitro and the copper release rate from resin matrices, as well as the correlation between the two variables. Different concentrations of copper iodide
Changfeng Li et al.
Developmental cell, 46(4), 441-455 (2018-08-14)
Pancreatic cancer is an aggressive malignancy with changes in the tumor microenvironment. Here, we demonstrate that PINK1 and PARK2 suppressed pancreatic tumorigenesis through control of mitochondrial iron-dependent immunometabolism. Using mouse models of spontaneous pancreatic cancer, we show that depletion of Pink1 and Park2

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