Passa al contenuto
Merck
Tutte le immagini(3)

Documenti fondamentali

Visualizza tutta la documentazione

MAK089

Sigma-Aldrich

γ-Glutamyltransferase (GGT) Activity Colorimetric Assay Kit

sufficient for 100 colorimetric tests

Sinonimo/i:

GGT Colorimetric Assay Kit

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(3)

About This Item

Codice UNSPSC:
12161503
NACRES:
NA.84

impiego

sufficient for 100 colorimetric tests

Metodo di rivelazione

colorimetric

Malattie correlate

cardiovascular diseases; neurological disorders; cancer; gastrointestinal diseases

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... GGT1(2678) , GGT2(728441) , GGT5(2687) , GGT6(124975) , GGT7(2686)
mouse ... GGT1(14598) , GGT5(23887) , GGT6(71522) , GGT7(207182)
rat ... GGT1(116568) , GGT5(29566) , GGT6(408206) , GGT7(156275)

Descrizione generale

γ-Glutamyltransferase (GGT, EC 2.3.2.2) is a membrane-bound protein that catalyzes the transfer of -glutamyl moieties to acceptor molecules such as amino acids or peptides. GGT plays a key role in the λ-glutamyl cycle, a critical pathway for glutathione homeostasis as well as the detoxification of xenobiotics. Serum GGT levels can be elevated in many pathophysiological conditions such as cardiovascular disease, chronic liver disease, and metabolic syndrome. Elevated serum levels of GGT can also be indicative of oxidative stress.

Applicazioni

γ-Glutamyltransferase (GGT) Activity Colorimetric Assay Kit has been used to assess the activity of γ-glutamyltransferase.

Caratteristiche e vantaggi

Compatible with high-throughput handling systems.

Compatibilità

Suitable for the measurement of gamma-glutamyl transferase (GGT) in a variety of samples including tissue, cells and serum

Principio

The GGT Activity Colorimetric Assay kit provides a simple and direct procedure for measuring GGT activity in a variety of samples. GGT activity is determined by a coupled enzyme assay, in which the GGT transfers the γ-glutamyl group from the substrate L-γ-Glutamyl-p-nitroanilide, liberating the chromogen p-nitroanilide (pNA, 418 nm) proportional to the GGT present. One unit of GGT is the amount of enzyme that will generate 1.0μmole of pNA per minute at 37 °C.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

188.6 °F - closed cup

Punto d’infiammabilità (°C)

87 °C - closed cup

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
8A24K07840
7K21K07840
7J30K07840
7B23K07840
6L24K07840

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBPα.
Bauer R C, et al.
The Journal of Clinical Investigation, 125(10), 3809-3818 (2015)
Eslam E Abd El-Fattah et al.
Frontiers in pharmacology, 12, 720173-720173 (2022-02-01)
HIF-1α is a key factor promoting the development of hepatocellular carcinoma (HCC). As well, AKT-AMPKα-mTOR signaling is a promising target for cancer therapy. Yet, the AKT-AMPKα-mTOR-dependent activation of HIF-1α has not been studied in livers with HCC. In addition, the
Robert C Bauer et al.
The Journal of clinical investigation, 125(10), 3809-3818 (2015-09-09)
Variants near the gene TRIB1 are significantly associated with several plasma lipid traits, circulating liver enzymes, and the development of coronary artery disease in humans; however, it is not clear how its protein product tribbles-1 regulates lipid metabolism. Here, we
Gamma-glutamyl transferases: A structural, mechanistic and physiological perspective.
Balakrishna S and Asmita A P
Frontiers in Biology, 9(1), 51-65 (2014)
A once-daily dose of tadalafil for erectile dysfunction: compliance and efficacy.
Washington III S L and Shindel A W
Drug design, development and therapy, 4, 159-159 (2010)
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.